Skip to main content

International Journal of Phytomedicine and Phytotherapy

Table 9 Effects of methanolic extracts of different plant parts of A. solanacea on Tail Immersion Test in mice

From: In-vivo and in-vitro evaluation of pharmacological activities of Ardisia solanacea leaf extract

Test samples

Dose (mg/kg)

Reaction times in seconds (Mean ± SEM) and % MPE

Pre-treatment

30 min

60 min

90 min

120 min

Control

0.25 ml/ 25 g b.w

2.8 ± 0.37

2.6 ± 0.24

(1.64%)

2 ± 0.32

(6.56%)

2.6 ± 0.24

(1.64%)

3 ± 0.32

(1.63%)

Standard

50

2.6 ± 0.40

5.6 ± 0.25##

(24.41%)

7.4 ± 0.24##

(38.70%)

8.8 ± 0.37***

(50.00%)

8.6 ± 0.40##

(48.38%)

ASME 200

200

2.4 ± 0.25

4.2 ± 0.37*

(14.28%)

6.2 ± 0.37##

(30.16%)

7.6 ± 0.40***

(41.27%)

7.8 ± 0.37##

(42.85%)

ASME 400

400

2.6 ± 0.40

5.2 ± 0.37##

(20.97%)

7.2 ± 0.37##

(37.09%)

8.6 ± 0.24***

(48.38%)

8.2 ± 0.20##

(45.16%)

ASNH 200

200

2.8 ± 0.37

3.6 ± 0.25

(6.55%)

4.4 ± 0.24##

(13.12%)

5.8 ± 0.37**

(24.59%)

6.8 ± 0.37##

(32.78%)

ASNH 400

400

2.2 ± 0.20

3.4 ± 0.24

(9.37%)

5.4 ± 0.25##

(25.00%)

6.4 ± 0.24***

(32.81%)

7.4 ± 0.25##

(40.63%)

ASCF 200

200

2 ± 0.00

5.2 ± 0.20##

(24.62%

7.2 ± 0.20##

(40.00%)

8.2 ± 0.20***

(47.69%)

8.8 ± 0.37##

(52.30%)

ASCF 400

400

2.2 ± 0.20

5.2 ± 0.20***

(23.44%)

8.4 ± 0.25***

(48.44%)

9.4 ± 0.24***

(56.25%)

9.2 ± 0.20***

(54.68%)

  1. Note: Each value represents the mean ± SEM. (n = 5). One- way ANOVA followed by Dunnett’s t test. ##p < 0.005, *p < 0.05 compared with control. ASME = methanolic extract of A. solanacea, ASCF = Chloroform soluble fraction, ASNH = n-hexane soluble fraction