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International Journal of Phytomedicine and Phytotherapy

Table 1 Effects of different extracts of L. alba in acetic acid-induced writhing test

From: In vivo and in silico evaluation of analgesic activity of Lippia alba

Treatment groupDosenNumber of writhingInhibition (%)
Control10 ml/kg556.5 ± 5.80
Standard (Diclofenac Sodium)100 mg/kg510.75 ± 3.83*78.61 ± 9.60*
ME250 mg/kg537.50 ± 1.70*a31.94 ± 5.80*
ME500 mg/kg527.00 ± 1.87*a49.30 ± 9.48*
PEE250 mg/kg536.25 ± 0.85*a33.89 ± 6.40*
PEE500 mg/kg526.00 ± 1.35*a53.09 ± 2.87*
DCME250 mg/kg537.5 ± 2.10*a30.89 ± 9.80*
DCME500 mg/kg527.50 ± 1.19*a50.09 ± 4.24*
  1. Number of writhing is present as mean ± standard error of mean. *P < 0.05, vs control (Dunnett’s t test); aP < 0.05, vs Standard group (pair-wise comparison by post-hoc Tukey’s HSD test). ME: methanolic extract; PEE: petroleum ether extract; DCME: dichloromethane extract