Pharmaceutical hit of anti type 2 Diabetes mellitus on the phenolic extract of Malaka (Phyllanthus emblica L.) flesh

Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 3 A number of cells on histology of kidney, pancreas, and liver rats in various treatments

Treatment	Histology of rat kidney		Histology of rat pancreas	Histology of rat liver
Treatment	Normal cells of renal tubules (cells, Mean ± SD)	Proximal renal necrosa tubules (cells, Mean ± SD)	Pancreatic β cells (cells, Mean ± SD)	Normal hepatocyte count (cell, Mean ± SD)	Necrosa hepatocytes (cells, Mean ± SD)
P0	560 ± 10,00^a	32 ± 2,08^d	450 ± 10,00^a	180 ± 10,00^a	13 ± 3,51^c
P1	435 ± 13,22^c	123 ± 4,72^a	420 ± 10,00^b	140 ± 10,00^b	30 ± 7,63^ab
P2	447 ± 11,50^c	103 ± 10,06^b	410 ± 11,53^b	123 ± 9,50^b	43 ± 10,14^a
P3	534 ± 10,00^b	76 ± 9,50^c	436 ± 15,82^ab	164 ± 12,50^a	25 ± 5,00^bc

P0 = the negative control, P1 = the positive control, P2 = the ethyl acetate extract of the Malaka flesh given a concentration of 100 mg/kg body weight, P3 = the ethyl acetate extract of the Malaka flesh given a concentration of 200 mg/kg body weight. Different letters showed significant differences among the group (p < 0.05)