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International Journal of Phytomedicine and Phytotherapy

Table 2 The Effect of daily pretreatment with frankincense oil (1000 mg/kg/day for 5 days) on the levels of malondialdehyde (MDA), nitric oxide (NO), and reduced glutathione (GSH) in the cortex, hippocampus and striatum of rat model of SE

From: Effect of frankincense oil on the neurochemical changes induced in rat model of status epilepticus

  

Control

Rat model of SE.

%D

Oil protected

%D

p-value

Cortex

MDA

(nmol/g)

7.51a ± 0.47 (8)

10.69b ± 1.08 (8)

+ 42.34

5.36a ± 0.67 (8)

−28.63

0.000

NO

(μmol/g)

0.04a ± 0.002 (8)

0.05b ± 0.005 (7)

+ 25

0.03a ± 0.002 (9)

−25

0.013

GSH

(mmol/g)

4.38a ± 0.12 (7)

3.75b ± 0.03 (6)

−14.38

4.74a ± 0.23 (8)

+ 8.22

0.002

Hippocampus

MDA

(nmol/g)

2.53a ± 0.28 (7)

17.17b ± 2.27 (8)

+ 578.66

6.62a ± 1.40 (7)

+ 161.66

0.000

NO

(μmol/g)

0.12a ± 0.01 (9)

0.24b ± 0.01 (8)

+ 100

0.15a ± 0.02 (8)

+ 25

0.000

GSH

(mmol/g)

12.60a ± 0.50 (7)

10.53b ± 0.07 (7)

−16.43

12.47a ± 0.54 (8)

−1.03

0.006

Striatum

MDA

(nmol/g)

1.61a ± 0.25 (8)

3.84b ± 0.90 (9)

+ 138.51

1.66a ± 0.24 (9)

+ 3.11

0.016

NO

(μmol/g)

0.11a ± 0.01 (6)

0.15b ± 0.02 (7)

+ 36.36

0.09ab ± 0.01 (9)

−18.18

0.003

GSH

(mmol/g)

15.62a ± 0.74 (6)

13.46b ± 0.39 (7)

−13.83

16.04a ± 0.44 (9)

+ 2.69

0.004

  1. Values represent mean ± S.E. with the number of animals between parentheses
  2. % D: % difference with respect to control values
  3. Different letters indicate significantly different means at p-value < 0.05
  4. Same letters indicate non significant changes