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International Journal of Phytomedicine and Phytotherapy

Table 3 The Effect of daily pretreatment with frankincense oil (1000 mg/kg/day for 5 days) on the levels of serotonin (5-HT), norepinephrine (NE) and dopamine (DA) in the cortex and striatum in rat model of SE

From: Effect of frankincense oil on the neurochemical changes induced in rat model of status epilepticus

  

Control

Rat model of SE.

%D

Oil protected

%D

p-value

Cortex

5-HT

(μg/g)

4.32a ± 0.09 (8)

3.48b ± 0.11 (7)

− 19.44

3.71b ± 0.22 (7)

− 14.12

0.002

NE

(μg/g)

0.34a ± 0.01 (7)

0.34a ± 0.01 (6)

0

0.32a ± 0.01 (8)

−5.88

0.147

DA

(μg/g)

1.81a ± 0.12 (8)

1.39b ± 0.04 (7)

−23.20

1.53ab ± 0.10 (7)

−15.47

0.015

Striatum

5-HT

(μg/g)

11.31a ± 0.81 (8)

7.41b ± 0.61 (7)

−34.48

9.67 a ± 0.62 (8)

− 14.50

0.003

NE

(μg/g)

0.96a ± 0.07 (8)

0.68b ± 0.04 (7)

−29.17

0.91a ± 0.09 (6)

−5.21

0.014

DA

(μg/g)

4.71a ± 0.17 (7)

3.80b ± 0.15 (6)

−19.32

3.59b ± 0.16 (8)

−23.78

0.000

  1. Values represent mean ± S.E. with the number of animals between parentheses
  2. % D: % difference with respect to control values
  3. Different letters indicate significantly different means at p-value < 0.05
  4. Same letters indicate non significant changes