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International Journal of Phytomedicine and Phytotherapy

Table 2 Effect of Vitellaria paradoxa on fasting blood glucose and serum insulin levels in alloxan-induced diabetic rats

From: Antidiabetic and antioxidant potentials of Vitellaria paradoxa barks in alloxan-induced diabetic rats

Group Blood glucose level (mg/gL) Insulin (μU/mL)
Day 0 Day 7 Day 14 Day 14
Normal control 80.4 ± 2.2 81.6 ± 7.5 83.4 ± 7.9 16.2 ± 1.0
Diabetic control 173.0 ± 2.1*** 173.0 ± 4.7*** 174.4 ± 4.4*** 6.1 ± 0.5***
Glibenclamide 2.5 mg/kg 153.8 ± 3.7*** 99.0 ± 7.8c 94.2 ± 7.8c 15.3 ± 1.1c
Extract 125 mg/kg 162.2 ± 11.9*** 139.2 ± 4.1***b 114.8 ± 9.9**c 10.5 ± 0.7**a
Extract 250 mg/kg 172.4 ± 8.2*** 111.0 ± 7.7*c 107.6 ± 7.2*c 13.2 ± 0.9c
Extract 500 mg/kg 165.2 ± 4.7*** 104.0 ± 7.6c 92.6 ± 8.2c 14.9 ± 0.8c
  1. Each value is expressed as mean ± S.E.M. (n = 5). *p < 0.05; **p < 0.01; ***p < 0.001 significantly different when compared to the normal control group. ap < 0.05; bp < 0.01; pp < 0.001 significantly different when compared to the diabetic control group