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Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 2 Effect of Vitellaria paradoxa on fasting blood glucose and serum insulin levels in alloxan-induced diabetic rats

From: Antidiabetic and antioxidant potentials of Vitellaria paradoxa barks in alloxan-induced diabetic rats

Group

Blood glucose level (mg/gL)

Insulin (μU/mL)

Day 0

Day 7

Day 14

Day 14

Normal control

80.4 ± 2.2

81.6 ± 7.5

83.4 ± 7.9

16.2 ± 1.0

Diabetic control

173.0 ± 2.1***

173.0 ± 4.7***

174.4 ± 4.4***

6.1 ± 0.5***

Glibenclamide 2.5 mg/kg

153.8 ± 3.7***

99.0 ± 7.8c

94.2 ± 7.8c

15.3 ± 1.1c

Extract 125 mg/kg

162.2 ± 11.9***

139.2 ± 4.1***b

114.8 ± 9.9**c

10.5 ± 0.7**a

Extract 250 mg/kg

172.4 ± 8.2***

111.0 ± 7.7*c

107.6 ± 7.2*c

13.2 ± 0.9c

Extract 500 mg/kg

165.2 ± 4.7***

104.0 ± 7.6c

92.6 ± 8.2c

14.9 ± 0.8c

  1. Each value is expressed as mean ± S.E.M. (n = 5). *p < 0.05; **p < 0.01; ***p < 0.001 significantly different when compared to the normal control group. ap < 0.05; bp < 0.01; pp < 0.001 significantly different when compared to the diabetic control group
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