International Journal of Phytomedicine and Phytotherapy
Table 3 Effect of Vitellaria paradoxa on glycogen content and some hepatic enzymes activities in alloxan-induced diabetic rats
Groups | Glycogen (mg/g tissue) | Fructose-1,6- biphosphatase (U/g protein) | Glucose-6-phosphatase (U/g protein) | Glucokinase (U/g protein) |
|---|---|---|---|---|
Normal control | 19.9 ± 2.2 | 154.7 ± 3.9 | 3.4 ± 0.3 | 0.34 ± 0.01 |
Diabetic control | 9.6 ± 1.2*** | 197.2 ± 4.2*** | 6.0 ± 0.6** | 0.20 ± 0.01*** |
Glibenclamide 2.5 mg/kg | 18.8 ± 1.1c | 163.1 ± 3.4c | 4.7 ± 0.4a | 0.31 ± 0.01c |
Extract 125 mg/kg | 14.4 ± 1.0* | 170.8 ± 6.8b | 5.3 ± 0.3 | 0.27 ± 0.03b |
Extract 250 mg/kg | 16.9 ± 1.0b | 167.5 ± 4.6b | 4.8 ± 0.6a | 0.34 ± 0.02c |
Extract 500 mg/kg | 16.8 ± 0.6b | 168.1 ± 4.1b | 4.1 ± 0.3a | 0.32 ± 0.02c |