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International Journal of Phytomedicine and Phytotherapy

Table 3 Effect of Vitellaria paradoxa on glycogen content and some hepatic enzymes activities in alloxan-induced diabetic rats

From: Antidiabetic and antioxidant potentials of Vitellaria paradoxa barks in alloxan-induced diabetic rats

Groups Glycogen
(mg/g tissue)
Fructose-1,6-
biphosphatase
(U/g protein)
Glucose-6-phosphatase
(U/g protein)
Glucokinase
(U/g protein)
Normal control 19.9 ± 2.2 154.7 ± 3.9 3.4 ± 0.3 0.34 ± 0.01
Diabetic control 9.6 ± 1.2*** 197.2 ± 4.2*** 6.0 ± 0.6** 0.20 ± 0.01***
Glibenclamide 2.5 mg/kg 18.8 ± 1.1c 163.1 ± 3.4c 4.7 ± 0.4a 0.31 ± 0.01c
Extract 125 mg/kg 14.4 ± 1.0* 170.8 ± 6.8b 5.3 ± 0.3 0.27 ± 0.03b
Extract 250 mg/kg 16.9 ± 1.0b 167.5 ± 4.6b 4.8 ± 0.6a 0.34 ± 0.02c
Extract 500 mg/kg 16.8 ± 0.6b 168.1 ± 4.1b 4.1 ± 0.3a 0.32 ± 0.02c
  1. Each value is expressed as mean ± S.E.M. (n = 5). *p < 0.05; **p < 0.01; ***p < 0.001 significantly different when compared to the normal control group. ap < 0.05; bp < 0.01; cp < 0.001 significantly different when compared to the diabetic control group