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International Journal of Phytomedicine and Phytotherapy

Table 4 Effect of Vitellaria paradoxa on lipid parameters in alloxan-induced diabetes in rats

From: Antidiabetic and antioxidant potentials of Vitellaria paradoxa barks in alloxan-induced diabetic rats

 

Total cholesterol

(mg/dL)

Triglycerides

(mg/dL)

HDL-c

(mg/dL)

LDL-c

(mg/dL)

Normal control

34.1 ± 2.1

24.4 ± 2.1

12.1 ± 2.6

17.1 ± 1.3

Diabetic control

44.5 ± 1.2*

34.6 ± 1.3*

10.7 ± 1.3

26.9 ± 1.6*

Glibenclamide 2.5 mg/kg

42.9 ± 3.4

20.2 ± 2.2b

23.4 ± 3.1*a

15.4 ± 0.8b

Extract 125 mg/kg

35.3 ± 1.7

23.6 ± 2.6a

14.3 ± 2.2

16.3 ± 2.4b

Extract 250 mg/kg

39.2 ± 1.1

22.7 ± 3.8a

18.1 ± 2.3

16.6 ± 2.8a

Extract 500 mg/kg

30.1 ± 2.6b

20.9 ± 1.7b

13.3 ± 1.1

13.4 ± 1.9c

  1. Each value is expressed as mean ± S.E.M. (n = 5). *p < 0.05 significantly different when compared to the normal control group. ap < 0.05; bp < 0.01; cp < 0.001 significantly different when compared to the diabetic control group