International Journal of Phytomedicine and Phytotherapy
Table 5 Anti-diarrheal activity study of PESF, DMSF and EASF by castor oil-induced diarrhea in mice
From: In vitro and in vivo evaluation of pharmacological potentials of Campsis radicans L
Treatment | % Reduction in the number of diarrheal feces in mice | |||
|---|---|---|---|---|
After 1 h | After 2 h | After 3 h | After 4 h | |
Loperamide (50 mg/kg b.w.) | 100 ± 0.00* | 90.09 ± 8.17** | 85.65 ± 5.83** | 74.96 ± 4.08** |
PESF (200 mg/kg b.w.) | 75.18 ± 20.41 | 79.88 ± 16.33* | 57.17 ± 10.10* | 65.07 ± 4.08** |
PESF (400 mg/kg b.w.) | 75.18 ± 20.41 | 90.09 ± 8.17** | 78.59 ± 0.00** | 80.06 ± 4.08** |
DMSF (200 mg/kg b.w.) | 75.18 ± 20.41 | 79.98 ± 8.17** | 57.17 ± 0.00** | 65.07 ± 4.08** |
DMSF (400 mg/kg b.w.) | 24.81 ± 35.36 | 60.06 ± 16.33 | 50.01 ± 5.83** | 65.07 ± 4.08** |
EASF (200 mg/kg b.w.) | – | 30.03 ± 8.17 | 35.76 ± 10.10 | 44.98 ± 8.16* |
EASF (400 mg/kg b.w.) | 75.18 ± 20.41 | 69.97 ± 0.00** | 50.01 ± 5.83** | 59.97 ± 4.08** |