Myocardial potency of Caesalpinia bonducella Linn. on doxorubicin induced myocardial infarction in albino rats

Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 1 Effect of aqueous extract of Caesalpinia bonducella L. (AECB) on activities of marker enzymes in serum of experimental animals

Groups	I	II	III	IV	V
CPK (μmol of creatine liberated/hr./L)	0.91 ±0.17	3.67 ±0.22^*a	2.56 ±0.24^**b	1.41 ±0.15^**b	1.25 ±0.11^*c
LDH (nm of pyruvate liberated/h/L)	178.24 ±2.42	298.34 ±3.14^*a	248.72 ±2.71^**b	197.33 ±2.45^**b	188.74 ±2.11^*c
CK MB (IU/dl)	33.33 ±10.33	93.33 ±3.56^*a	116.5 ±6.86^**b	63 ±6.26^**b	49 ±3.99^*c
Troponin (mg/dl)	0.52 ±0.07	1.80 ±0.07^*a	1.38 ±0.06^**b	0.79 ±0.06^**b	0.7 ±0.06^*c

Values are mean ± S.E.M (n = 6)
^a*P < 0.05 statistically significant when disease control(Group II) compared with normal control (Group I),^b**P < 0.05 statistically significant when AECB treated (Group III,IV) compared with disease control groups(group II),^c*P < 0.05 statistically significant when AECB treated (Group III,IV) compared with standard drug treated(Group V)