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International Journal of Phytomedicine and Phytotherapy

Table 4 Effect of Lophira lanceolata leaf extract on atherogenic/dyslipidemic indices in rats administered cisplatin

From: Protective effect of aqueous extract of Lophira lanceolata leaf against cisplatin-induced hepatorenal injuries and dyslipidemia in Wistar rats

Treatment groups

Atherogenic/dyslipidemic indices of rats

Cardiac risk ratio (CRR)

Atherogenic coefficient (AC)

Atherogenic index (AIP)

Classical ratio (CR)

Normal control

3.17

2.17

0.55

1.27

Cisplatin control

5.31 (67)a

4.31 (98)a

0.61 (11)a

3.64 (186)a

200 mg/kg LLE only

3.44 (9)a

2.44 (12)a

0.50 (9)a

1.59 (25)a

400 mg/kg LLE only

2.33 (27)a

1.33 (39)a

0.53 (4)a

1.39 (9)a

200 mg/kg LLE + CIS

2.64 (50)b

1.64 (62)b

0.55 (10)b

0.76 (79)b

400 mg/kg LLE + CIS

3.65 (31)b

2.65 (39)b

0.56 (8)b

2.27 (38)b

  1. Values are means of 5 rats; Values in parenthesis are percentage changes (%), CIS - Cisplatin, LLE - Lophira lanceolata leaf extract
  2. apercentage changes when compared with normal control
  3. bpercentage decrease when compared with cisplatin control