International Journal of Phytomedicine and Phytotherapy
Table 6 Cytotoxic effect of S.macranthum Fruit methanol extract (SFME) on MDA-MB-231 and MEF-L929 cell line
From: In-vitro cytotoxic effects of Solanum macranthum fruit. Dunal extract with antioxidant potential
MDA-MB-231 | MEF-L929 | |||
|---|---|---|---|---|
Concentration μg/ml | Absorbance at 630 nm | % of Viability | Absorbance at 630 nm | % of Viability |
Blank | 0.04 ± 0.01 | – | 0.04 ± 0.01 | – |
Control | 1.13 ± 0.15** | 100 | 0.61 ± 0.01** | 100 |
100 | 1.08 ± 0.16* | 96.27 | 0.90 ± 0.01** | 98.29 |
200 | 0.96 ± 0.14* | 84.74 | 0.85 ± 0.01** | 91.93 |
300 | 0.75 ± 0.06** | 64.89 | 0.80 ± 0.01** | 86.87 |
400 | 0.55 ± 0.02** | 47.08 | 0.75 ± 0.01** | 80.17 |
500 | 0.29 ± 0.01** | 23.14 | 0.68 ± 0.01** | 73.29 |
Camptothecin (15uM) | 0.61 ± 0.09* | 52.51 | 0.92 ± 0.01** | 64.26 |