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International Journal of Phytomedicine and Phytotherapy

Table 5 Effect of L. pinnatifidum on carrageenan-induced paw edema in rats

From: Evaluation of antioxidant and anti-inflammatory potency of Lepidium pinnatifidum Ledeb

TreatmentEdema formation to %inhibition
1 h2 h3 h4 h
Dic. Pot. (10 mg/kg)0.777 ± 0.033
23.702 ± 3.291fghi
0.594 ± 0.064
24.910 ± 8.118e
0.481 ± 0.044
45.819 ± 4.966de
0.12 ± 0.027
81.081 ± 4.269a
LPM (400 mg/kg)0.671 ± 0.047
34.018 ± 4.654bcd
0.455 ± 0.043
42.419 ± 5.500bc
0.38 ± 0.050
57.234 ± 5.664bc
0.175 ± 0.015
72.297 ± 2.385abc
LPM (200 mg/kg)0.68 ± 0.033
33.240 ± 3.305cde
0.484 ± 0.022
38.808 ± 2.811cd
0.464 ± 0.035
47.749 ± 3.997de
0.267 ± 0.021
57.882 ± 3.370def
LPH (400 mg/kg)0.563 ± 0.048
44.642 ± 4.712a
0.355 ± 0.030
55.108 ± 3.837a
0.245 ± 0.027
72.395 ± 3.140a
0.125 ± 0.067
80.247 ± 10.629a
LPH (200 mg/kg)0.595 ± 0.011
41.514 ± 1.113ab
0.422 ± 0.013
46.570 ± 1.743abc
0.375 ± 0.013
57.717 ± 1.572bc
0.197 ± 0.024
68.918 ± 3.831bc
LPC (400 mg/kg)0.705 ± 0.027
30.715 ± 2.709def
0.48 ± 0.02
39.350 ± 2.527cd
0.418 ± 0.032
52.893 ± 3.642cd
0.2 ± 0.032
68.468 ± 5.149bc
LPC (200 mg/kg)0.751 ± 0.033
26.227 ± 3.325efg
0.541 ± 0.027
31.588 ± 3.531de
0.522 ± 0.043
41.157 ± 4.893ef
0.3 ± 0.020
52.702 ± 3.281ef
LPE (400 mg/kg)0.598 ± 0.031
41.234 ± 3.074ab
0.392 ± 0.019
50.361 ± 2.496ab
0.317 ± 0.053
64.308 ± 6.050ab
0.15 ± 0.043
76.351 ± 6.811ab
LPE (200 mg/kg)0.628 ± 0.060
38.289 ± 5.929abc
0.461 ± 0.044
41.696 ± 5.623bc
0.434 ± 0.038
51.125 ± 4.351cd
0.23 ± 0.036
63.738 ± 5.756cd
LPB (400 mg/kg)0.761 ± 0.040
25.245 ± 3.985fgh
0.494 ± 0.042
37.545 ± 5.353cd
0.474 ± 0.036
46.623 ± 4.102de
0.237 ± 0.029
62.612 ± 4.615cde
LPB (200 mg/kg)0.788 ± 0.035
22.580 ± 3.513ghi
0.574 ± 0.034
27.436 ± 4.368e
0.558 ± 0.027
37.138 ± 3.077fg
0.33 ± 0.021
47.972 ± 3.405fg
LPA
(400 mg/kg)
0.801 ± 0.046
21.318 ± 4.584 hi
0.541 ± 0.022
31.588 ± 2.865de
0.531 ± 0.026
40.192 ± 3.007ef
0.27 ± 0.020
57.432 ± 3.281def
LPA (200 mg/kg)0.852 ± 0.031
16.269 ± 3.089i
0.612 ± 0.036
22.563 ± 4.597e
0.61 ± 0.037
31.350 ± 4.210g
0.368 ± 0.030
41.891 ± 4.853g
  1. Data values shown represent Mean ± SD and percentage inhibition at different concentrations; (n = 7). Different superscript (a-i) indicate significance at P < 0.05. LPM: L. pinnatifidum Methanol fraction. LPH: L. pinnatifidum n-Hexane fraction. LPC: L. pinnatifidum Chloroform fraction. LPE: L. pinnatifidum Ethyl acetate fraction. LPB: L. pinnatifidum Butanol fraction. LPA: L. pinnatifidum Aqueous fraction