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International Journal of Phytomedicine and Phytotherapy

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Table 3 Effect of combined administration of lisinopril and ethanolic bark extract of E. chlorantha on serum urea, creatinine, Na+ and K+ level in type 2 diabetes rats

From: Toxicological evaluations of combined administration of ethanolic stem bark extract of Enantia chlorantha and lisinopril in experimental type 2 diabetes

GroupsTreatmentsUrea (mg/ml)Creatinine (mg/ml)Sodium (Na+) (mmol/L)Potassium (K+) (mmol/L)
NCDistilled water13.30 ± 2.67a1.030 ± 0.19a1.384 ± 0.94a3.54 ± 1.19a
DMSTZ-fructose+ distilled water45.69 ± 1.07b3.169 ± 1.06b0.965 ± 0.78b10.10 ± 0.90b
T1Extract only19.89 ± 3.12c1.269 ± 0.46a1.375 ± 0.44a6.63 ± 1.65a
T2Glucophage only27.44 ± 4.21c1.948 ± 0.44a1.255 ± 0.86a7.60 ± 0.74a
T3Extract + Lisinopril15.56 ± 3.91a1.069 ± 0.93a1.177 ± 1.46a5.16 ± 1.16a
T4Glucophage + Lisinopril18.82 ± 4.14a1.459 ± 0.37a1.153 ± 1.14a6.43 ± 1.89a
T5Lisinopril only12.84 ± 0.83a1.392 ± 0.48a1.364 ± 0.61a5.51 ± 0.62a
  1. Results are mean ± SD of seven determinations
  2. Values in the same column with similar superscripts (a, b or c) are not significantly (p > 0.05) different from each other