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International Journal of Phytomedicine and Phytotherapy

Table 2 Effect of CSE and NLE on liver and kidney antioxidant enzymes activities in DF-exposed rats

From: Comparative study of the effects of Cassia spectabilis and Newbouldia laevis leaf extracts on diclofenac-induced hepatorenal oxidative damage in rats

Treatment groups Levels of liver and kidney antioxidant enzymes in rats
Catalase (μmol/min/mg p) SOD (μmol/min/mg p) GPx (μmol/min/mg p) GST (μmol/min/mg p)
Liver
 I. Normal saline 12.55 ± 0.03 14.27 ± 0.15 11.04 ± 0.05 43.07 ± 0.11
 II. DF + Saline 3.72 ± 0.09a 4.42 ± 0.02a 1.81 ± 0.03a 18.11 ± 0.11a
 III. CSE + DF 10.91 ± 0.01b 11.99 ± 0.06b 7.87 ± 0.02b 35.25 ± 0.41b
 IV. NLE + DF 9.38 ± 0.02b 5.28 ± 0.02b 3.86 ± 0.02b 21.36 ± 0.21b
Kidney
 I. Normal saline 3.12 ± 0.01 11.24 ± 0.13 9.46 ± 0.05 16.91 ± 0.25
 II. DF + Saline 0.89 ± 0.02a 3.16 ± 0.03a 1.28 ± 0.05a 4.13 ± 0.09a
 III. CSE + DF 2.81 ± 0.05b 9.52 ± 0.12b 7.21 ± 0.05b 14.66 ± 0.14b
 IV. NLE + DF 1.19 ± 0.02b 4.25 ± 0.02b 3.79 ± 0.01b 8.03 ± 0.03b
  1. Values are Mean ± SEM, n = 6; P Protein, DF Diclofenac sodium, asignificantly different from normal control (p < 0.01), bsignificantly different from DF control (p < 0.01)