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International Journal of Phytomedicine and Phytotherapy

Table 3 Effect of CSE and NLE on levels of Proteins, MDA, GSH and G6Pase in hepatorenal tissues of DF-exposed rats

From: Comparative study of the effects of Cassia spectabilis and Newbouldia laevis leaf extracts on diclofenac-induced hepatorenal oxidative damage in rats

Treatment groups Levels of hepatorenal oxidative injuries markers in rats
MDA (nmol/mg p) Protein (g/L) GSH (μg/mg p) G6Pase (U/mg p)
Liver
 I. Normal saline 1.99 ± 0.01 164.41 ± 0.29 64.65 ± 0.18 28.82 ± 0.25
 II. DF + Saline 15.43 ± 0.19a 121.07 ± 0.06a 30.30 ± 0.23a 14.62 ± 0.02a
 III. CSE + DF 7.11 ± 0.01b 148.16 ± 0.10b 52.48 ± 0.25b 21.03 ± 0.03b
 IV. NLE + DF 11.10 ± 0.06b 135.40 ± 0.16b 39.15 ± 0.08b 14.04 ± 0.04a
Kidney
 I. Normal saline 1.75 ± 0.03 163.11 ± 0.30 12.46 ± 0.2 23.55 ± 0.43
 II. DF + Saline 8.68 ± 0.20a 82.73 ± 0.47a 4.76 ± 0.03a 9.59 ± 0.12a
 III. CSE + DF 3.23 ± 0.10b 144.52 ± 0.29b 9.04 ± 0.04b 17.28 ± 0.22b
 IV. NLE + DF 6.12 ± 0.01b 132.14 ± 0.21b 5.34 ± 0.03b 11.01 ± 0.02b
  1. Values are Mean ± SEM, n = 6; DF Diclofenac sodium, asignificantly different from normal control (p < 0.01), bsignificantly different from diclofenac control (p < 0.01)