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Table 3 Effect of CSE and NLE on levels of Proteins, MDA, GSH and G6Pase in hepatorenal tissues of DF-exposed rats

From: Comparative study of the effects of Cassia spectabilis and Newbouldia laevis leaf extracts on diclofenac-induced hepatorenal oxidative damage in rats

Treatment groups

Levels of hepatorenal oxidative injuries markers in rats

MDA (nmol/mg p)

Protein (g/L)

GSH (μg/mg p)

G6Pase (U/mg p)

Liver

 I. Normal saline

1.99 ± 0.01

164.41 ± 0.29

64.65 ± 0.18

28.82 ± 0.25

 II. DF + Saline

15.43 ± 0.19a

121.07 ± 0.06a

30.30 ± 0.23a

14.62 ± 0.02a

 III. CSE + DF

7.11 ± 0.01b

148.16 ± 0.10b

52.48 ± 0.25b

21.03 ± 0.03b

 IV. NLE + DF

11.10 ± 0.06b

135.40 ± 0.16b

39.15 ± 0.08b

14.04 ± 0.04a

Kidney

 I. Normal saline

1.75 ± 0.03

163.11 ± 0.30

12.46 ± 0.2

23.55 ± 0.43

 II. DF + Saline

8.68 ± 0.20a

82.73 ± 0.47a

4.76 ± 0.03a

9.59 ± 0.12a

 III. CSE + DF

3.23 ± 0.10b

144.52 ± 0.29b

9.04 ± 0.04b

17.28 ± 0.22b

 IV. NLE + DF

6.12 ± 0.01b

132.14 ± 0.21b

5.34 ± 0.03b

11.01 ± 0.02b

  1. Values are Mean ± SEM, n = 6; DF Diclofenac sodium, asignificantly different from normal control (p < 0.01), bsignificantly different from diclofenac control (p < 0.01)