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International Journal of Phytomedicine and Phytotherapy

Table 2 α-Amylase inhibition (IC50) and binding affinities of methanolic extracts (Ki) and their DPPH radical scavenging (antioxidant) activities

From: Evaluation of the alpha-amylase inhibitory activity of Nepalese medicinal plants used in the treatment of diabetes mellitus

 

α-Amylase inhibition (μg/mL)

Antioxidant activity (μg/mL)

Plant

IC50 value

Ki value

Type of inhibition

IC50 value

Acacia catechu

49.9 ± 0.4

26.6 ± 6.7

Mixed

3.9 ± 0.3

Dioscorea bulbifera

413.5 ± 11.1

384.6 ± 36.8

Mixed

49.3 ± 3.6

Swertia chirata

296.1 ± 8.7

204.2 ± 17.9

Mixed

53.6 ± 2.7

Acarbosea

6.1 ± 0.1

Quercetinb

2.3 ± 0.1

  1. Acarbosea was used as the standard for α-amylase inhibition
  2. Quercetinb was used as the standard for radical scavenging activity