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International Journal of Phytomedicine and Phytotherapy

Table 1 Hepatoprotective effect of ALME on different biochemical parameters in cadmium induced liver damage in rats

From: Protective effect of Antigonon leptopus (Hook et. Arn) in cadmium induced hepatotoxicity and nephrotoxicity in rats

Experimental GroupsAST (U/L)ALT (U/L)ALP (U/L)TB (mg/dl)DB (mg/dl)TP (g/dl)ALB (g/dl)
Normal51.81 ± 3.5652.7 ± 1.9119.5 ± 3.230.21 ± 0.040.07 ± 0.049.94 ± 0.355.89 ± 0.53
Toxic (Cd) (5 mg/kg)83.62 ± 2.38135.78 ± 4.3168.3 ± 7.511.03 ± 0.141.04 ± 0.074.37 ± 0.393.07 ± 0.25
Silymarin (100 mg/kg)55.31 ± 2.53**
(88.99%)
63.15 ± 4.5**
(87.42%)
127.3 ± 3.51**
(84.01%)
0.30 ± 0.08**
(89.02%)
0.27 ± 0.03**
(79.38%)
9.36 ± 0.49**
(89.58%)
4.94 ± 0.52**
(66.31%)
ALME (100 mg/kg)70.15 ± 4.12*
(42.34%)
80.03 ± 6.11*
(67.10%)
145.5 ± 8.4*
(46.72%)
0.66 ± 0.05*
(45.12%)
0.55 ± 0.03*
(50.51%)
7.97 ± 0.4*
(64.63%)
4.48 ± 0.23*
(50.70%)
ALME (200 mg/kg)62.79 ± 5.21**
(65.48%)
65.58 ± 7.7**
(84.49%)
132.4 ± 4.14**
(73.56%)
0.48 ± 0.09**
(67.07%)
0.39 ± 0.03**
(67.01%)
9.07 ± 0.58**
(84.38%)
4.8 ± 0.48**
(61.34%)
ALME (400 mg/kg)68.53 ± 3.18*
(47.43%)
74.13 ± 1.68**
(74.20%)
139.11 ± 5.9**
(59.83%)
0.53 ± 0.08**
(60.97%)
0.42 ± 0.04**
(63.91%)
8.39 ± 0.36**
(72.17%)
4.66 ± 0.23*
(56.38%)
  1. Values are expressed as mean ± SD, n = 6. **P < 0.01, *P < 0.05. P value- Control versus other groups.