Skip to main content

International Journal of Phytomedicine and Phytotherapy

Table 1 Hepatoprotective effect of ALME on different biochemical parameters in cadmium induced liver damage in rats

From: Protective effect of Antigonon leptopus (Hook et. Arn) in cadmium induced hepatotoxicity and nephrotoxicity in rats

Experimental Groups

AST (U/L)

ALT (U/L)

ALP (U/L)

TB (mg/dl)

DB (mg/dl)

TP (g/dl)

ALB (g/dl)

Normal

51.81 ± 3.56

52.7 ± 1.9

119.5 ± 3.23

0.21 ± 0.04

0.07 ± 0.04

9.94 ± 0.35

5.89 ± 0.53

Toxic (Cd) (5 mg/kg)

83.62 ± 2.38

135.78 ± 4.3

168.3 ± 7.51

1.03 ± 0.14

1.04 ± 0.07

4.37 ± 0.39

3.07 ± 0.25

Silymarin (100 mg/kg)

55.31 ± 2.53**

(88.99%)

63.15 ± 4.5**

(87.42%)

127.3 ± 3.51**

(84.01%)

0.30 ± 0.08**

(89.02%)

0.27 ± 0.03**

(79.38%)

9.36 ± 0.49**

(89.58%)

4.94 ± 0.52**

(66.31%)

ALME (100 mg/kg)

70.15 ± 4.12*

(42.34%)

80.03 ± 6.11*

(67.10%)

145.5 ± 8.4*

(46.72%)

0.66 ± 0.05*

(45.12%)

0.55 ± 0.03*

(50.51%)

7.97 ± 0.4*

(64.63%)

4.48 ± 0.23*

(50.70%)

ALME (200 mg/kg)

62.79 ± 5.21**

(65.48%)

65.58 ± 7.7**

(84.49%)

132.4 ± 4.14**

(73.56%)

0.48 ± 0.09**

(67.07%)

0.39 ± 0.03**

(67.01%)

9.07 ± 0.58**

(84.38%)

4.8 ± 0.48**

(61.34%)

ALME (400 mg/kg)

68.53 ± 3.18*

(47.43%)

74.13 ± 1.68**

(74.20%)

139.11 ± 5.9**

(59.83%)

0.53 ± 0.08**

(60.97%)

0.42 ± 0.04**

(63.91%)

8.39 ± 0.36**

(72.17%)

4.66 ± 0.23*

(56.38%)

  1. Values are expressed as mean ± SD, n = 6. **P < 0.01, *P < 0.05. P value- Control versus other groups.