International Journal of Phytomedicine and Phytotherapy
Table 4 ADME and toxic properties
From: Antioxidant and in vivo hepatoprotective effects of Gardenia gummifera L.f. fruit methanol extract
ADME | Toxicity | ||||||||
|---|---|---|---|---|---|---|---|---|---|
Compound name | Chemspider ID | HIA (%) | PPB (%) | BBB (%) | Cacok2 (nm/sec) | Skin Permeability | MDCK (nm/sec) | Rodent Carcinogenicity | |
Carcino Mouse | Carcino Rat | ||||||||
Silymarine | 78.55 | 87.70 | 0.0596 | 7.852 | −4.236 | 0.0691 | negative | negative | |
 I | 106,997 | 75.91 | 38.437 | 0.273 | 1.85622 | −4.75733 | 24.0956 | negative | negative |
 II | 26,000,801 | 89.88 | 2.783 | 0.511 | 7.647 | −2.61671 | 158.521 | negative | positive |
 II | 10,246,715 | 20.28 | 6.595 | 0.428 | 8.27242 | −4.96717 | 0.530 | negative | positive |