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International Journal of Phytomedicine and Phytotherapy

Fig. 2 | Clinical Phytoscience

Fig. 2

From: Self-emulsifying formulation of Spinacia oleracea reduces the dose and escalates bioavailability of bioactive compounds to accelerate fracture repair in rats

Fig. 2

DSE and FDSE improved micro-architectural parameters in the drill-hole site and accelerates bone regeneration at the fracture site. Representative 2D (a) and 3D (b) images generated by micro-CT showing bone healing at different doses. Micro-CT analysis showing (c) bone volume/tissue volume BV/TV; (d) trabecular number (Tb.N); (e) trabecular separation (Tb.Sp); (f) structure model index (SMI). All values are expressed as Mean ± SEM (n = 10 rats/group).*p < 0.05, **p < 0.01, ***p < 0.001 compared with control. #p < 0.05, ##p < 0.01, ###p < 0.001 compared to formulated extract (FDSE) with corresponding dose of extract (DSE).@p < 0.05, @@p < 0.01, @@@p < 0.001 compared to PTH

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