Characterization of anti-plasmodial, analgesic and anti-inflammatory fraction of Maytenus senegalensis (lam.) Exell leaf extract in mice

Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 2 Antiplasmodial activity of purified fraction of M. senegalensis leaf against Plasmodium berghei Infected mice

	Doses (mg/kg bw)	1	2	3	4	5	6	Mean Parasitaemia	% suppression
MS	75	60.36	66.25	70.25	64.25	65.25	78.25	67.83 ± 5.43	44.25 ± 3.21^a
	150	28.25	34.05	36.25	29.05	34.05	38.25	33.17 ± 3.45	72.74 ± 6.54 ^b
	300	30.05	34.05	25.05	26.25	32.25	26.05	26.83 ± 2.90	76.30 ± 8.32 ^b
CQ	5	15.05	18.36	26.25	31.25	16.25	20.05	21.05 ± 3.45	82.74 ± 7.56 ^c
NS	2 ml/kg	122.05	120.07	115	116.25	131.25	126.67	121.67 ± 7.54

Data are MEAN ± SEM of triplicate determinations. Values followed by different superscript are significantly different (p < 0.05)
MS: Maytenus senegalensis (Lam.) Exell
CQ: Chloroquine
NS: Normal saline