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International Journal of Phytomedicine and Phytotherapy

Table 2 Antiplasmodial activity of purified fraction of M. senegalensis leaf against Plasmodium berghei Infected mice

From: Characterization of anti-plasmodial, analgesic and anti-inflammatory fraction of Maytenus senegalensis (lam.) Exell leaf extract in mice

  Doses (mg/kg bw) 1 2 3 4 5 6 Mean Parasitaemia % suppression
MS 75 60.36 66.25 70.25 64.25 65.25 78.25 67.83 ± 5.43 44.25 ± 3.21a
  150 28.25 34.05 36.25 29.05 34.05 38.25 33.17 ± 3.45 72.74 ± 6.54 b
  300 30.05 34.05 25.05 26.25 32.25 26.05 26.83 ± 2.90 76.30 ± 8.32 b
CQ 5 15.05 18.36 26.25 31.25 16.25 20.05 21.05 ± 3.45 82.74 ± 7.56 c
NS 2 ml/kg 122.05 120.07 115 116.25 131.25 126.67 121.67 ± 7.54  
  1. Data are MEAN ± SEM of triplicate determinations. Values followed by different superscript are significantly different (p < 0.05)
  2. MS: Maytenus senegalensis (Lam.) Exell
  3. CQ: Chloroquine
  4. NS: Normal saline