|
Doses (mg/kg bw)
|
1
|
2
|
3
|
4
|
5
|
6
|
Mean Parasitaemia
|
% suppression
|
---|
MS
|
75
|
60.36
|
66.25
|
70.25
|
64.25
|
65.25
|
78.25
|
67.83 ± 5.43
|
44.25 ± 3.21a
|
|
150
|
28.25
|
34.05
|
36.25
|
29.05
|
34.05
|
38.25
|
33.17 ± 3.45
|
72.74 ± 6.54 b
|
|
300
|
30.05
|
34.05
|
25.05
|
26.25
|
32.25
|
26.05
|
26.83 ± 2.90
|
76.30 ± 8.32 b
|
CQ
|
5
|
15.05
|
18.36
|
26.25
|
31.25
|
16.25
|
20.05
|
21.05 ± 3.45
|
82.74 ± 7.56 c
|
NS
|
2 ml/kg
|
122.05
|
120.07
|
115
|
116.25
|
131.25
|
126.67
|
121.67 ± 7.54
| |
- Data are MEAN ± SEM of triplicate determinations. Values followed by different superscript are significantly different (p < 0.05)
- MS: Maytenus senegalensis (Lam.) Exell
- CQ: Chloroquine
- NS: Normal saline