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International Journal of Phytomedicine and Phytotherapy

Table 2 Antiplasmodial activity of purified fraction of M. senegalensis leaf against Plasmodium berghei Infected mice

From: Characterization of anti-plasmodial, analgesic and anti-inflammatory fraction of Maytenus senegalensis (lam.) Exell leaf extract in mice

 

Doses (mg/kg bw)

1

2

3

4

5

6

Mean Parasitaemia

% suppression

MS

75

60.36

66.25

70.25

64.25

65.25

78.25

67.83 ± 5.43

44.25 ± 3.21a

 

150

28.25

34.05

36.25

29.05

34.05

38.25

33.17 ± 3.45

72.74 ± 6.54 b

 

300

30.05

34.05

25.05

26.25

32.25

26.05

26.83 ± 2.90

76.30 ± 8.32 b

CQ

5

15.05

18.36

26.25

31.25

16.25

20.05

21.05 ± 3.45

82.74 ± 7.56 c

NS

2 ml/kg

122.05

120.07

115

116.25

131.25

126.67

121.67 ± 7.54

 
  1. Data are MEAN ± SEM of triplicate determinations. Values followed by different superscript are significantly different (p < 0.05)
  2. MS: Maytenus senegalensis (Lam.) Exell
  3. CQ: Chloroquine
  4. NS: Normal saline