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International Journal of Phytomedicine and Phytotherapy

Fig. 5 | Clinical Phytoscience

Fig. 5

From: Bridelia ferruginea Benth leaves attenuates diabetes nephropathy in STZ-induced rats via targeting NGAL/KIM-1/cystatin c gene

Fig. 5

(a-c): Gene expression of kidney tissues from STZ-induced diabetes rats treated with petroleum and diethyl ether fractions of B. ferruginea Benth (a) Neutrophil gelatinase associated lipocalin (NGAL) gene expression (b) Kidney injury molecule-1 (KIM-1) gene expression (c) Cystatin C gene expression. Group 1: Normal Control animals. Group 2: STZ-induced animals administered 2 ml/kg b.w. of Normal saline. Group 3: STZ-induced animals treated with 5 mg/kg b.w. of metformin. Group 4: STZ-induced animals treated with 100 mg/kg b.w. of petroleum ether fraction of B. ferruginea. Group 5: STZ-induced animals treated with 200 mg/kg b.w. of petroleum ether fraction of B. ferruginea. Group 6: STZ-induced animals treated with 100 mg/kg b.w. of Diethyl ether fraction of B. ferruginea. Group 7: STZ-induced animals treated with 200 mg/kg b.w. of Diethyl ether fraction of B. ferruginea

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