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Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 4 Lipid peroxidation and antioxidant enzymes activities in the liver and kidney of test and control animals

From: Ethanol extract of Nigella sativa has antioxidant and ameliorative effect against nickel chloride-induced hepato-renal injury in rats

SN

Treatment

LMDA

KMDA

LCAT

KCAT

LGST

KGST

1

Water

2.82. ± 0.27

3.62 ± 0.32

36.50 ± 0.33

335.85 ± 16.85

3.34 ± 0.18

34.16 ± 9.64

2

NiCl2

4.84 ± 0.58

5.15 ± 0.55*

11.19 ± 2.29*

201.16 ± 23.58

2.57 ± 0.04*

72.99 ± 7.78*

3

ENS

2.94 ± 0.53

3.41 ± 0.43

22.44 ± 4.63

328.63 ± 37.84

3.02 ± 0.38

46. 01 ± 3.99

4

ENS + NiCl2

3.78 ± 0.45

3.74 ± 0.30#

22.56 ± 6.74

306.60 ± 32.30

2.81 ± 0.20

39.17 ± 3.35#

  1. * Significantly different from control
  2. # Significantly different from NiCl2-treated rats
  3. Key:
  4. LMDA Liver Malonaldehyde (nmol/min/mg liver weight)
  5. KMDA Kidney Malonaldehyde (nmol/min/mg kidney weight)
  6. LCAT Liver Catalase activity (μmol/min/g liver weight)
  7. KCAT Kidney Catalase activity (μmol/min/g kidney weight)
  8. LGST Liver Glutathione-S-transferase (mmol/min/g liver weight)
  9. KGST Kidney Glutathione-S-transferase (mmol/min/g kidney weight)
  10. ENS Ethanol extract of Nigella sativa (50 mg/kg body weight)
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