Effect of hydro-methanol stem bark extract of Burkea africana on erythrocyte osmotic fragility and haematological parameters in acetaminophen-poisoned rats

Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 1 Haematological parameters of acetaminophen-poisoned rats treated with MSBEBA

Parameters	Normal Control	PCM Control	MSBEBA + PCM
Parameters	Normal Control	PCM Control	200 mg/kg	400 mg/kg	600 mg/kg
PCV (%)	42.67 ± 1.05^b	34.75 ± 0.25^a	41.00 ± 1.10^b	44.20 ± 1.16^b	43.20 ± 1.50^b
HB (g/dL)	14.60 ± 0.29^b	12.00 ± 0.10^a	14.04 ± 0.46^b	14.92 ± 0.38^b	14.04 ± 0.22^b
RBC (X10¹²/L)	7.55 ± 0.24^b	6.63 ± 0.10^a	6.77 ± 0.05^a	8.24 ± 0.16^c	7.13 ± 0.15^ab
MCV (FL)	56.68 ± 1.44^ab	52.45 ± 1.13^a	60.60 ± 1.61^b	53.62 ± 0.67^a	60.63 ± 2.19^b
MCH (Pg)	19.39 ± 0.33^ab	18.11 ± 0.40^a	20.74 ± 0.60^b	18.11 ± 0.38^a	19.72 ± 0.57^ab
MCHC (g/dL)	34.25 ± 0.43^a	34.54 ± 0.25^a	34.24 ± 0.60^a	33.78 ± 0.53^a	32.62 ± 1.00^a
TWBC (X/10¹²/L)	7.86 ± 0.23^abc	7.92 ± 0.49^abc	7.04 ± 0.26^a	8.53 ± 0.39^bc	7.42 ± 0.58^ab
Neutrophils (%)	33.83 ± 0.40^bc	35.00 ± 1.00^c	35.40 ± 1.08^c	22.80 ± 1.32^a	24.60 ± 0.24^a
Lymphocytes (%)	66.50 ± 0.50^a	66.25 ± 0.75 ^a	65.60 ± 0.5^a	79.20 ± 0.80^c	75.80 ± 1.07^b
Eosinohpils (%)	0.83 ± 0.40^ab	1.00 ± 0.40^b	0.20 ± 0.20^ab	0.40 ± 0.24^ab	0.20 ± 0.20^ab

Values are Mean ± SEM. n = 6. Values with different superscript on the same row are significantly (P < 0.05)