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International Journal of Phytomedicine and Phytotherapy

Table 3 Effects of ethanolic extract T. indica L. leaf on food intake and body weight of high-fat diet induced rats

From: Antioxidant-rich Tamarindus indica L. leaf extract reduced high-fat diet-induced obesity in rat through modulation of gene expression

Parameter

ND

HFD

HFD + TILE100

HFD + TILE200

HFD + TILE400

Food intake (g/day)

18.23 ± 2.51a

18.51 ± 3.11a

20.21 ± 2.42a

19.41 ± 2.92a

19.21 ± 2.67a

Percent weight gain

39.82 ± 4.25a

66.27 ± 5.42b

62.91 ± 7.38b

59.72 ± 5.32b

45.26 ± 4.53a

Liver weight (g/100 g body weight)

3.12 ± 0.43a

4.83 ± 0.63b

4.64 ± 0.54b

4.52 ± 0.57b

3.61 ± 0.61a

Epidedymal fat (g/100 g body weight)

1.13 ± 0.12a

1.81 ± 0.23b

1.72 ± 0.18b

1.64 ± 0.19b

1.61 ± 0.17b

Mesenteric fat (g/100 g body weight)

0.73 ± 0.08a

1.17 ± 0.13b

1.02 ± 0.12b

0.97 ± 0.10a

0.84 ± 0.11a

Peritoneal fat (g/100 g body weight)

0.87 ± 0.10a

1.26 ± 0.15b

1.22 ± 0.11b

1.17 ± 0.13b

0.91 ± 0.12a

  1. Effects of Tamarindus indica L. leaf extract (TILE) on food intake, body weight gain, liver weight and adipose tissue weight in different group of Wistar rats fed with either of standard laboratory diet (SD), or high-fat diet (HFD), or HFD with TILE. TILE was given orally everyday throughout the study period either in low dose (HFD + TILE100), or intermediate dose (HFD + TILE200) or high dose (HFD + TILE400). Data was analyzed by one way ANOVA followed by Newman-Keuls’s post-hoc test and expressed as mean ± SEM (n = 6). Values with different superscript letters within the same row are significantly different at p < 0.05