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International Journal of Phytomedicine and Phytotherapy

Table 4 Effect of high-fat diet and ethanolic extract of T. indica L. leaf on lipid profile of rats

From: Antioxidant-rich Tamarindus indica L. leaf extract reduced high-fat diet-induced obesity in rat through modulation of gene expression

Parameter

ND

HFD

HFD + TILE100

HFD + TILE200

HFD + TILE400

TG (mg/dl)

121.81 ± 13.33a

216.37 ± 21.57b

211.42 ± 22.17b

199.43 ± 23.63b

145.82 ± 19.23a

TC (mg/dl)

198.21 ± 23.84a

274.23 ± 25.34b

268.05 ± 31.34b

242.54 ± 34.39b

205.35 ± 24.47a

HDL-C (mg/dl)

62.33 ± 6.72a

41.27 ± 6.98b

47.64 ± 7.45b

50.67 ± 5.43b

51.31 ± 6.53b

LDL-C (mg/dl)

111.27 ± 14.58a

189.71 ± 17.32b

178.87 ± 19.37b

152.21 ± 19.34a

125.56 ± 14.49a

VLDL-C (mg/dl)

24.52 ± 3.65a

43.34 ± 5.67b

42.13 ± 6.37b

39.72 ± 5.43b

29.22 ± 4.51a

AI

2.19 ± 0.21a

5.65 ± 0.71b

4.58 ± 0.63b

3.84 ± 0.34c

3.05 ± 0.42c

CRI

3.19 ± 0.61a

6.65 ± 0.81b

5.58 ± 0.71b

4.84 ± 0.37c

4.05 ± 0.54a

  1. Effects of T. indica L. leaf extract (TILE) on lipid related parameters in different group of Wistar rats fed with either of standard laboratory diet (SD), or high-fat diet (HFD), or HFD with TILE. TILE was given orally everyday throughout the study period either in low dose (HFD + TILE100), or intermediate dose (HFD + TILE200) or high dose (HFD + TILE400). Data was analyzed by one way ANOVA followed by Newman-Keuls’s post-hoc test and expressed as mean ± SEM (n = 6). Values with different superscript letters within the same row are significantly different at p < 0.05