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International Journal of Phytomedicine and Phytotherapy

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Table 4 Effect of high-fat diet and ethanolic extract of T. indica L. leaf on lipid profile of rats

From: Antioxidant-rich Tamarindus indica L. leaf extract reduced high-fat diet-induced obesity in rat through modulation of gene expression

Parameter ND HFD HFD + TILE100 HFD + TILE200 HFD + TILE400
TG (mg/dl) 121.81 ± 13.33a 216.37 ± 21.57b 211.42 ± 22.17b 199.43 ± 23.63b 145.82 ± 19.23a
TC (mg/dl) 198.21 ± 23.84a 274.23 ± 25.34b 268.05 ± 31.34b 242.54 ± 34.39b 205.35 ± 24.47a
HDL-C (mg/dl) 62.33 ± 6.72a 41.27 ± 6.98b 47.64 ± 7.45b 50.67 ± 5.43b 51.31 ± 6.53b
LDL-C (mg/dl) 111.27 ± 14.58a 189.71 ± 17.32b 178.87 ± 19.37b 152.21 ± 19.34a 125.56 ± 14.49a
VLDL-C (mg/dl) 24.52 ± 3.65a 43.34 ± 5.67b 42.13 ± 6.37b 39.72 ± 5.43b 29.22 ± 4.51a
AI 2.19 ± 0.21a 5.65 ± 0.71b 4.58 ± 0.63b 3.84 ± 0.34c 3.05 ± 0.42c
CRI 3.19 ± 0.61a 6.65 ± 0.81b 5.58 ± 0.71b 4.84 ± 0.37c 4.05 ± 0.54a
  1. Effects of T. indica L. leaf extract (TILE) on lipid related parameters in different group of Wistar rats fed with either of standard laboratory diet (SD), or high-fat diet (HFD), or HFD with TILE. TILE was given orally everyday throughout the study period either in low dose (HFD + TILE100), or intermediate dose (HFD + TILE200) or high dose (HFD + TILE400). Data was analyzed by one way ANOVA followed by Newman-Keuls’s post-hoc test and expressed as mean ± SEM (n = 6). Values with different superscript letters within the same row are significantly different at p < 0.05