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International Journal of Phytomedicine and Phytotherapy

Table 5 Protective effect of methanol extract of A. vulgaris leaves extract on tail withdrawal reflexes induced by tail immersion method in mice

From: Phytochemical and pharmacological activities of methanol extract of Artemisia vulgaris L. leaves

Groups Treatment Dose (mg/kg b. wt) Reaction time in seconds at time (minutes) (mean ± sem)
basal time 10 15 30 60
Control Normal saline ….. 1.10 ± 0.577 1.40 ± 0.115 1.60 ± 0.264 1.834 ± 0.230 2.734 ± 0.757
Std. Drugs Indomethacin 10 1.47 ± 0.272 2.534 ± 145* 3.334 ± 0.230* 4.10 ± 0.200* 5.134 ± 0.351*
Test 1 MEAV 200 1.067 ± 0.881 1.50 ± 0.300 1.734 ± 0.152 2.367 ± 0.208* 2.90 ± 0.200*
Test 2 MEAV 400 1.234 ± 0.120 2.067 ± 0.208* 2.834 ± 0.251* 3.034 ± 0.152* 3.40 ± 0.300*
One way ANOVA F value 1.319 14.136 40.778 71.556 17.509
P value 0.334 <  0.001 <  0.0001 <  0.0001 <  0.001
  1. Each value was the mean ± SEM for 6mice, *P ≤ 0.05, compared with control. Data were analyzed by using One-way ANOVA followed by Duncan’s multiple comparison tests