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International Journal of Phytomedicine and Phytotherapy

Table 5 Protective effect of methanol extract of A. vulgaris leaves extract on tail withdrawal reflexes induced by tail immersion method in mice

From: Phytochemical and pharmacological activities of methanol extract of Artemisia vulgaris L. leaves

Groups

Treatment

Dose (mg/kg b. wt)

Reaction time in seconds at time (minutes) (mean ± sem)

basal time

10

15

30

60

Control

Normal saline

…..

1.10 ± 0.577

1.40 ± 0.115

1.60 ± 0.264

1.834 ± 0.230

2.734 ± 0.757

Std. Drugs

Indomethacin

10

1.47 ± 0.272

2.534 ± 145*

3.334 ± 0.230*

4.10 ± 0.200*

5.134 ± 0.351*

Test 1

MEAV

200

1.067 ± 0.881

1.50 ± 0.300

1.734 ± 0.152

2.367 ± 0.208*

2.90 ± 0.200*

Test 2

MEAV

400

1.234 ± 0.120

2.067 ± 0.208*

2.834 ± 0.251*

3.034 ± 0.152*

3.40 ± 0.300*

One way ANOVA

F value

1.319

14.136

40.778

71.556

17.509

P value

0.334

<  0.001

<  0.0001

<  0.0001

<  0.001

  1. Each value was the mean ± SEM for 6mice, *P ≤ 0.05, compared with control. Data were analyzed by using One-way ANOVA followed by Duncan’s multiple comparison tests