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International Journal of Phytomedicine and Phytotherapy

Table 2 Effect of herbal ointment on immunological markers in excision wounded animals

From: Wound healing potentials of herbal ointment containing Calendula officinalis Linn. on the alteration of immunological markers and biochemical parameters in excision wounded animals

Groups

Interleukin − 6 (IL – 6) (pg/ml)

Platelet Derived Growth Factors (PDGF)(pg/ml)

Tumor Necrosis Factor - alpha (TNF - α) (pg/ml)

Epidernmal Growth Factor (EGF) (pg/ml)

I

2650 ± 1.05

16.20 ± 0.08

22.58 ± 0.05

48.80 ± 0.45

II

13,500 ± 2.30 a*

3.25 ± 0.01 a*

183.75 ± 1.50 a*

12.50 ± 0.06 a*

III

5500 ± 1.25 b*

11.61 ± 0.06 b*

82.56 ± 0.80 b*

40.21 ± 0.08 b*

IV

2700 ± 0.98 b*

15.21 ± 0.05 b*

28.56 ± 0.20 b*

46.52 ± 0.07 b*

V

2540 ± 0.53 c*

15.95 ± 0.05 c*

30.55 ± 0.08 c*

44.50 ± 0.15 c*

  1. Values are expressed as mean ± SEM n = 6.
  2. a*P < 0.05 statistically significant when excision wound control (Group II) compared with normal group (Group I),b**P < 0.05 statistically significant when HO treated (Group III,IV) compared with excision wound control groups (group II), c*P < 0.05 statistically significant when HO treated (Group III, IV) compared with Reference ointment treated (Group V)