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International Journal of Phytomedicine and Phytotherapy

Table 1 Dosing protocol of polyherbal combination (PHC) to female swiss albino mice for acute and sub-acute toxicity study

From: An exploratory analysis on the toxicity & safety profile of Polyherbal combination of curcumin, quercetin and rutin

S.No

Group name

Group detail

Dosing schedule

Acute toxicity study

 1

NC

Normal Control of acute toxicity study

Normal Saline

 2

TG1

Acute toxicity group 1

250 mg/kg/day/p.o

 3

TG2

Acute toxicity group 2

500 mg/kg/day/p.o

 4

TG3

Acute toxicity group 3

1000 mg/kg/day/p.o

 5

TG4

Acute toxicity group 4

2000 mg/kg/day/p.o

Sub-acute toxicity study

 1

NCX

Normal Control of sub-acute toxicity study

Normal Saline

 2

TX1

Sub-acute toxicity group 1

250 mg/kg/day/p.o

 3

TX2

Sub-acute toxicity group 2

500 mg/kg/day/p.o

 4

TX3

Sub-acute toxicity group 3

1000 mg/kg/day/p.o

 5

TX4

Sub-acute toxicity group 4

2000 mg/kg/day/p.o