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International Journal of Phytomedicine and Phytotherapy

Table 4 Effect of oral administration of polyherbal combination (PHC) on relative organ weight (g) of mice

From: An exploratory analysis on the toxicity & safety profile of Polyherbal combination of curcumin, quercetin and rutin

Organ Relative organ weight (gm)
Distilled water 250 mg/kg/day 500 mg/kg/day 1000 mg/kg/day 2000 mg/kg/day
NCX TX1 TX2 TX3 TX4
Brain 1.874 ± 0.220 1.816 ± 0.208 1.795 ± 0.108 1.804 ± 0.161 1.842 ± 0.142
Heart 0.875 ± 0.040 0.85 ± 0.005 0.851 ± 0.068 0.851 ± 0.078 0.879 ± 0.069
Kidney (L + R) 1.249 ± 0.075 1.222 ± 0.046 1.4 ± 0.253 1.214 ± 0.113 1.26 ± 0.117
Liver 6.024 ± 0.431 5.91 ± 0.074 5.822 ± 0.348 5.793 ± 0.433 6.059 ± 0.470
Lung 1.293 ± 0.068 1.294 ± 0.043 1.274 ± 0.063 1.249 ± 0.098 1.303 ± 0.092
  1. The values were depicted as means ± SD for 5 mice per group. Statistically significant differences between groups were measured using one-way ANOVA with nonparametric paired t-test. The values in different treated groups were found to be non-significant (p > 0.05) when compared to normal control group (NCX)