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International Journal of Phytomedicine and Phytotherapy

Table 5 Effect of polyherbal combination (PHC) on hematological parameter

From: An exploratory analysis on the toxicity & safety profile of Polyherbal combination of curcumin, quercetin and rutin

Organ Hematological parameter
Distilled water 250 mg/kg/day 500 mg/kg/day 1000 mg/kg/day 2000 mg/kg/day
NCX TX1 TX2 TX3 TX4
Neutrophils (%) 17.597 ± 0.272 17.637 ± 0.631 17.703 ± 0.666 17.693 ± 0.836 18.333 ± 0.917
Lymphocyte (%) 78.267 ± 0.074 78.313 ± 0.264 78.357 ± 0.329 78.39 ± 0.349 78.34 ± 0.161
Monocyte (%) 2.673 ± 0.245 2.66 ± 0.510 2.597 ± 0.405 2.763 ± 0.636 2.657 ± 0.448
Reticulocyte (%) 1.5 ± 0.282 1.517 ± 0.168 1.59 ± 0.176 1.553 ± 0.222 1.537 ± 0.318
RBC (106/μL) 7.567 ± 0.254 7.583 ± 0.105 7.623 ± 0.136 7.427 ± 0.212 7.607 ± 0.240
WBC (103/μL) 8.8 ± 0.819 8.823 ± 1.043 8.867 ± 1.076 8.883 ± 0.982 8.86 ± 1.223
Platelet (103/μL) 1048.667 ± 24.338 1055.667 ± 54.077 1059.667 ± 61.158 1064.667 ± 66.109 1057.667 ± 53.116
PCV (L/L) 43.3 ± 0.248 43.337 ± 0.409 43.44 ± 0.447 43.39 ± 0.501 43.37 ± 0.244
MCV (L/L) 58.313 ± 0.333 58.353 ± 0.528 58.393 ± 0.585 58.417 ± 0.625 58.367 ± 0.388
MCH (pg) 20.047 ± 0.174 20.263 ± 0.289 20.163 ± 0.145 20.147 ± 0.261 20.277 ± 0.460
MCHC (g/μl) 32.4430.331 32.483 ± 0.542 32.677 ± 0.746 32.52 ± 0.609 32.507 ± 0.589
Eosinophil’s (%) 1.613 ± 0.320 1.627 ± 0.368 1.56 ± 0.236 1.677 ± 0.485 1.65 ± 0.197
Basophils (%) 0.513 ± 0.025 0.553 ± 0.100 0.583 ± 0.035 0.583 ± 0.067 0.573 ± 0.064
Hematocrit (%) 41.39 ± 0.383 41.42 ± 0.171 41.507 ± 0.264 41.473 ± 0.251 41.44 ± 0.128
Hemoglobin (%) 14.467 ± 0.352 14.553 ± 0.439 14.613 ± 0.593 14.547 ± 0.705 14.587 ± 0.292
  1. The values were depicted as means ± SD for 5 mice per group. Statistically significant differences between groups were measured using one-way ANOVA with nonparametric paired t- test. The values in different treated groups were found to be non-significant (p > 0.05) when compared to normal control group (NCX)