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International Journal of Phytomedicine and Phytotherapy

Table 5 Effect of polyherbal combination (PHC) on hematological parameter

From: An exploratory analysis on the toxicity & safety profile of Polyherbal combination of curcumin, quercetin and rutin

Organ

Hematological parameter

Distilled water

250 mg/kg/day

500 mg/kg/day

1000 mg/kg/day

2000 mg/kg/day

NCX

TX1

TX2

TX3

TX4

Neutrophils (%)

17.597 ± 0.272

17.637 ± 0.631

17.703 ± 0.666

17.693 ± 0.836

18.333 ± 0.917

Lymphocyte (%)

78.267 ± 0.074

78.313 ± 0.264

78.357 ± 0.329

78.39 ± 0.349

78.34 ± 0.161

Monocyte (%)

2.673 ± 0.245

2.66 ± 0.510

2.597 ± 0.405

2.763 ± 0.636

2.657 ± 0.448

Reticulocyte (%)

1.5 ± 0.282

1.517 ± 0.168

1.59 ± 0.176

1.553 ± 0.222

1.537 ± 0.318

RBC (106/μL)

7.567 ± 0.254

7.583 ± 0.105

7.623 ± 0.136

7.427 ± 0.212

7.607 ± 0.240

WBC (103/μL)

8.8 ± 0.819

8.823 ± 1.043

8.867 ± 1.076

8.883 ± 0.982

8.86 ± 1.223

Platelet (103/μL)

1048.667 ± 24.338

1055.667 ± 54.077

1059.667 ± 61.158

1064.667 ± 66.109

1057.667 ± 53.116

PCV (L/L)

43.3 ± 0.248

43.337 ± 0.409

43.44 ± 0.447

43.39 ± 0.501

43.37 ± 0.244

MCV (L/L)

58.313 ± 0.333

58.353 ± 0.528

58.393 ± 0.585

58.417 ± 0.625

58.367 ± 0.388

MCH (pg)

20.047 ± 0.174

20.263 ± 0.289

20.163 ± 0.145

20.147 ± 0.261

20.277 ± 0.460

MCHC (g/μl)

32.4430.331

32.483 ± 0.542

32.677 ± 0.746

32.52 ± 0.609

32.507 ± 0.589

Eosinophil’s (%)

1.613 ± 0.320

1.627 ± 0.368

1.56 ± 0.236

1.677 ± 0.485

1.65 ± 0.197

Basophils (%)

0.513 ± 0.025

0.553 ± 0.100

0.583 ± 0.035

0.583 ± 0.067

0.573 ± 0.064

Hematocrit (%)

41.39 ± 0.383

41.42 ± 0.171

41.507 ± 0.264

41.473 ± 0.251

41.44 ± 0.128

Hemoglobin (%)

14.467 ± 0.352

14.553 ± 0.439

14.613 ± 0.593

14.547 ± 0.705

14.587 ± 0.292

  1. The values were depicted as means ± SD for 5 mice per group. Statistically significant differences between groups were measured using one-way ANOVA with nonparametric paired t- test. The values in different treated groups were found to be non-significant (p > 0.05) when compared to normal control group (NCX)