Skip to main content

International Journal of Phytomedicine and Phytotherapy

Table 6 Effect of polyherbal combination (PHC) on biochemical parameter

From: An exploratory analysis on the toxicity & safety profile of Polyherbal combination of curcumin, quercetin and rutin

Organ

Biochemical parameter

Distilled water

250 mg/kg/day

500 mg/kg/day

1000 mg/kg/day

2000 mg/kg/day

NCX

TX1

TX2

TX3

TX4

SGOT or AST (IU/L)

74.64 ± 3.821

75.207 ± 3.490

75.097 ± 2.531

75.583 ± 1.765

74.82 ± 3.810

SGPT or ALT (IU/L)

43.987 ± 3.185

44.39 ± 2.811

44.46 ± 3.438

45.27 ± 3.222

43.707 ± 1.262

GGT (IU/L)

0.417 ± 0.035

0.423 ± 0.040

0.427 ± 0.035***

0.433 ± 0.021

0.417 ± 0.038

ALP (IU/L)

564.26 ± 24.783

565.32 ± 24.716

565.153 ± 23.846

565.953 ± 24.871

571.453 ± 28.153

  1. The values were depicted as means ± SD for 5 mice per group. Statistically significant differences between groups were measured using one-way ANOVA with nonparametric paired t- test. Where ***p < 0.001, highly significant; when the values was compared with normal control group (NCX)