Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 8 Effect of polyherbal combination (PHC) on kidney function test

From: An exploratory analysis on the toxicity & safety profile of Polyherbal combination of curcumin, quercetin and rutin

Organ	Kidney function test
	Distilled water	250 mg/kg/day	500 mg/kg/day	1000 mg/kg/day	2000 mg/kg/day
	NCX	TX1	TX2	TX3	TX4
Total Bilirubin (mg/dL)	0.513 ± 0.031	0.513 ± 0.031	0.543 ± 0.050	0.527 ± 0.025	0.513 ± 0.038
Glucose (mg/dL)	133.667 ± 6.807	135 ± 5.240	135.687 ± 6.846***	135.303 ± 4.559	134.31 ± 3.822
BUN (mg/dL)	16.53 ± 0.407	16.553 ± 0.323	16.703 ± 0.355	16.633 ± 0.224	16.31 ± 0.375
Creatinine (mg/dL)	0.44 ± 0.111	0.463 ± 0.105	0.470 ± 0.135	0.477 ± 0.106*	0.437 ± 0.129
Sodium (mmol/L)	134.51 ± 1.43	133.63 ± 0.88	135.82 ± 1.05	134.12 ± 1.53	136.47 ± 1.83
Urea (mg/dL)	47.84 ± 2.44	46.91 ± 1.69	46.07 ± 2.19	47.99 ± 1.89	48.53 ± 2.59
Uric acid (mg/dL)	2.04 ± 0.41	2.33 ± 0.52	2.67 ± 0.69	2.61 ± 0.24	2.83 ± 0.84

The values were depicted as means ± SD for 5 mice per group. Statistically significant differences between groups were measured using one-way ANOVA with nonparametric paired t- test
Where ***p < 0.001, highly significant; *p < 0.05, significant when the values was compared with normal control group (NCX)

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