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International Journal of Phytomedicine and Phytotherapy

Table 4 Clinical studies of GeloMyrtol and cineole

From: Evidence-based management of acute rhinosinusitis with herbal products

Study Product Study design Population Sample size Main findings
Federspil P, et al. 1997 [37] GeloMyrtol Double-blind randomized clinical trial Acute sinusitis n = 331 Main study outcomes:
Changes in symptom score from baseline were greater with GeloMyrtol and an undefined essential oil than placebo.
Kehrl W, et al. 2004 [38] Cineole Double-blind randomized clinical trial Acute non-purulent rhinosinusitis n = 76 with cineole
n = 76 with placebo
Primary outcome:
The change in symptoms-sum-score from baseline to Day 7 was greater in the cineole group (− 12.5 ± 3.6) than in the placebo group (− 6.5 ± 3.5) (p < 0.0001).
Secondary outcome:
Changes in individual components of symptom-sum score were higher in the cineole group than in the placebo group