International Journal of Phytomedicine and Phytotherapy
Table 4 Clinical studies of GeloMyrtol and cineole
From: Evidence-based management of acute rhinosinusitis with herbal products
Study | Product | Study design | Population | Sample size | Main findings |
|---|---|---|---|---|---|
Federspil P, et al. 1997 [37] | GeloMyrtol | Double-blind randomized clinical trial | Acute sinusitis | n = 331 | Main study outcomes: Changes in symptom score from baseline were greater with GeloMyrtol and an undefined essential oil than placebo. |
Kehrl W, et al. 2004 [38] | Cineole | Double-blind randomized clinical trial | Acute non-purulent rhinosinusitis | n = 76 with cineole n = 76 with placebo | Primary outcome: The change in symptoms-sum-score from baseline to Day 7 was greater in the cineole group (− 12.5 ± 3.6) than in the placebo group (− 6.5 ± 3.5) (p < 0.0001). Secondary outcome: Changes in individual components of symptom-sum score were higher in the cineole group than in the placebo group |