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International Journal of Phytomedicine and Phytotherapy

Table 3 Lipinski rule

From: In-Vitro antioxidant, anti-lipid peroxidative activities and In-Silico study of Terminalia chebula bioactive compounds

  MW AlogP Hdon Hacc OB (%) Caco-2 BBB DL FASA- TPSA
Caffeic acid 180.17 1.37 3 4 54.97 0.27 0.11 0.05 0 77.76
Catechin 290.29 1.92 5 6 54.83 −0.03 −0.73 0.24 0 110.38
ellagic acid 302.2 1.48 4 8 43.06 −0.44 −1.41 0.43 0.43 141.34
epicatechin 290.29 1.92 5 6 48.96 0.02 −0.64 0.24 0.34 110.38
gallic acid 170.13 0.63 4 5 31.69 −0.09 −0.54 0.04 0.41 97.99
Quercetin 302.25 1.5 5 7 46.43 0.05 −0.77 0.28 0.38 131.36
Rutin 610.57 −1.45 10 16 3.2 −1.93 −2.75 0.68 0 269.43