Skip to main content

International Journal of Phytomedicine and Phytotherapy

Table 4 Effects of JCEE on protein and antioxidant system in liver and kidney of healthy wistar rats

From: Safety assessment of oral administration of ethanol extract of Justicia carnea leaf in healthy wistar rats: hematology, antioxidative and histology studies

Groups Organ Total protein (g/l) GSH (μmol/g of protein) CAT (U/g of protein) SOD (U/g of protein) MDA (μmol/g of protein) × 103
Control (1 ml dH2O) Liver 50.86 ± 3.99 0.87 ± 0.11 3.00 ± 0.10 1.97 ± 1.08 29.81 ± 4.84
Kidney 61.49 ± 19.91 1.09 ± 0.37 3.08 ± 1.24 4.25 ± 0.58 16.19 ± 3.76
50 (mg/kg) Liver 50.52 ± 8.74 0.84 ± 0.06 3.57 ± 1.74 2.36 ± 0.74 26.15 ± 2.36
Kidney 52.85 ± 8.59 0.71 ± 0.14 3.98 ± 1.07 3.21 ± 0.44 20.01 ± 3.03
100 (mg/kg) Liver 49.53 ± 2.72 0.48 ± 0.09 1.91 ± 0.95 2.51 ± 1.42 27.66 ± 10.49
Kidney 49.86 ± 4.35 0.61 ± 0.09 3.57 ± 0.14 1.44 ± 0.52 15.17 ± 4.05
500 (mg/kg) Liver 43.54 ± 3.32 0.68 ± 0.19 3.37 ± 0.83 3.79 ± 0.59 42.85 ± 5.49
Kidney 49.19 ± 1.33 0.99 ± 0.17 3.10 ± 0.58 4.56 ± 1.62 19.05 ± 8.45
800 (mg/kg) Liver 42.89 ± 2.64 0.78 ± 0.08 2.93 ± 0.13 3.53 ± 1.29 43.70 ± 4.28
Kidney 50.19 ± 2.66 0.85 ± 0.16 3.83 ± 0.27 1.00 ± 0.35* 23.01 ± 8.86
1200 (mg/kg) Liver 38.22 ± 3.52* 0.86 ± 0.19 3.65 ± 0.81 5.38 ± 2.06* 48.98 ± 5.66 *
Kidney 52.85 ± 3. 50 0.48 ± 0.02* 3.80 ± 0.47 3.97 ± 3.56 23.35 ± 8.33
  1. Data are presented as mean ± SEM: n = 5 determinations. Values with asterisk (*) in the same column indicate significant difference (p < 0.05) compared to control