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International Journal of Phytomedicine and Phytotherapy

Table 3 In vitro inhibitory effects of different solvent fractions fractions of P. guineense on α- glucosidase activity

From: In vitro antidiabetic potentials, antioxidant activities and phytochemical profile of african black pepper (Piper guineense)

Fraction Concentration(mg/ml) % Inhibition ± SEM IC50 (mg/ml) ± SEM
AQUEOUS 5.00 69.91 ± 0.01 2.90 ± 0.43
2.50 61.44 ± 0.40
1.25 54.77 ± 0.30
0.625 52.97 ± 0.20
0.3125 21.98 ± 0.68
0.15625 17.66 ± 0.67
BUTANOL 5.00 62.33 ± 2.06 0.83 ± 0.15
2.50 58.90 ± 2.96
1.25 57.10 ± 2.84
0.625 51.66 ± 6.30
0.3125 36.34 ± 7.25
0.15625 21.77 ± 3.36
DCM 5.00 70.30 ± 2.57 1.91 ± 0.03
2.50 56.91 ± 3.35
1.25 54.94 ± 2.47
0.625 47.23 ± 2.47
0.3125 30.80 ± 1.03
0.15625 27.03 ± 0.10
ETHYLACETATE 5.00 82.32 ± 2.87 0.24 ± 0.07
2.50 74.19 ± 3.56
1.25 63.06 ± 0.27
0.625 61.80 ± 0.66
0.3125 56.75 ± 0.93
0.15625 40.53 ± 1.25
ACARBOSE 5.00 23.81 ± 1.15 1.46 ± 0.21
2.50 22.08 ± 0.75
1.25 20.35 ± 0.43
0.625 17.75 ± 0.43
0.3125 12.55 ± 0.12
0.15625 10.02 ± 0.07