International Journal of Phytomedicine and Phytotherapy
Table 3 In vitro inhibitory effects of different solvent fractions fractions of P. guineense on α- glucosidase activity
Fraction | Concentration(mg/ml) | % Inhibition ± SEM | IC50 (mg/ml) ± SEM |
|---|---|---|---|
AQUEOUS | 5.00 | 69.91 ± 0.01 | 2.90 ± 0.43 |
2.50 | 61.44 ± 0.40 | ||
1.25 | 54.77 ± 0.30 | ||
0.625 | 52.97 ± 0.20 | ||
0.3125 | 21.98 ± 0.68 | ||
0.15625 | 17.66 ± 0.67 | ||
BUTANOL | 5.00 | 62.33 ± 2.06 | 0.83 ± 0.15 |
2.50 | 58.90 ± 2.96 | ||
1.25 | 57.10 ± 2.84 | ||
0.625 | 51.66 ± 6.30 | ||
0.3125 | 36.34 ± 7.25 | ||
0.15625 | 21.77 ± 3.36 | ||
DCM | 5.00 | 70.30 ± 2.57 | 1.91 ± 0.03 |
2.50 | 56.91 ± 3.35 | ||
1.25 | 54.94 ± 2.47 | ||
0.625 | 47.23 ± 2.47 | ||
0.3125 | 30.80 ± 1.03 | ||
0.15625 | 27.03 ± 0.10 | ||
ETHYLACETATE | 5.00 | 82.32 ± 2.87 | 0.24 ± 0.07 |
2.50 | 74.19 ± 3.56 | ||
1.25 | 63.06 ± 0.27 | ||
0.625 | 61.80 ± 0.66 | ||
0.3125 | 56.75 ± 0.93 | ||
0.15625 | 40.53 ± 1.25 | ||
ACARBOSE | 5.00 | 23.81 ± 1.15 | 1.46 ± 0.21 |
2.50 | 22.08 ± 0.75 | ||
1.25 | 20.35 ± 0.43 | ||
0.625 | 17.75 ± 0.43 | ||
0.3125 | 12.55 ± 0.12 | ||
0.15625 | 10.02 ± 0.07 |