International Journal of Phytomedicine and Phytotherapy
Table 4 Summary of studies on herbal-antimalarial drugs interactions in human volunteers and in-vitro studies
From: Antimalarial herbal drugs: a review of their interactions with conventional antimalarial drugs
S/no | Medicinal plant | Conventional antimalarial drug | Interaction effect | Reference |
|---|---|---|---|---|
1 | Garcinia kola seed (12.5 g) | Quinine sulphate (600 mg/kg) | ↓ in peak plasma concentration of quinine and its metabolites | [43] |
2 | Kola nut (12.5 g) | Halofantrine (500 mg) | ↓ in plasma concentrations of halofantrine and its active metabolite | [44] |
3 | Garcinia kola seed | Quinine: HPLC quantitative study | Quinine was adsorbed on G. kola (indicating antagonism) | [19] |