International Journal of Phytomedicine and Phytotherapy
Table 1 Dose values and activity level for determining ED50 of dry combined extract BNO 1016 in rats according to anti-inflammatory activity by Probit analysis
Dose, mg/kg | Activity, % | Dose variable, х | Probit, y | Weighing factor, В | хВ | х2В | YB | xyB |
|---|---|---|---|---|---|---|---|---|
after 1 h | ||||||||
15.0 | 8.0 | 3 | 3.6 | 2.3 | 6.9 | 20.7 | 8.28 | 24.84 |
50.0 | 27.0 | 10 | 4.39 | 4.3 | 43.0 | 430.0 | 18.88 | 188.77 |
150.0 | 42.0 | 30 | 4.80 | 4.8 | 144.0 | 4320.0 | 23.04 | 691.20 |
Sum | 11.4 | 193.9 | 4770.7 | 50.20 | 904.81 | |||
after 2 h | ||||||||
15.0 | 15.0 | 3 | 3.96 | 3.5 | 10.5 | 31.5 | 13.86 | 41.58 |
50.0 | 40.0 | 10 | 4.75 | 4.8 | 48.0 | 480.0 | 22.80 | 228.00 |
150.0 | 58.0 | 30 | 5.20 | 4.8 | 144.0 | 4320.0 | 24.96 | 748.80 |
Sum | 13.1 | 202.5 | 4831.5 | 61.62 | 1018.38 | |||