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International Journal of Phytomedicine and Phytotherapy

Table 2 Effect of methanolic extract of U. lobata on acute oral toxicity test in Swiss albino mice

From: Anxiolytic-like effect of Urena lobata (L.) in swiss albino mice

Observed parameters

Responses

0 mg/kg

1000 mg/kg

2000 mg/kg

3000 mg/kg

4000 mg/kg

Alertness

N

N

N

N

N

Grooming

A

A

A

A

A

Restlessness

A

A

A

A

A

Touch response

N

N

N

N

N

Torch response

N

N

N

N

N

Pain response

N

N

N

No

N

Tremors

A

A

A

A

A

Convulsion

A

A

A

A

A

Righting reflux

N

N

N

N

N

Gripping

N

N

N

N

N

Pinna reflex

P

P

P

P

P

Corneal reflex

P

P

P

P

P

Writhing

A

A

A

A

A

Pupils

N

N

N

N

N

Urination

N

N

N

N

N

Salivation

N

N

N

N

N

Skin color

N

N

N

N

N

Lacrimation

N

N

N

N

N

Food intake

N

N

N

N

N

Water intake

N

N

N

N

N

Mortality

-

-

-

-

-

  1. N Normal, A Absent, P Present, (-) – Nil