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International Journal of Phytomedicine and Phytotherapy

Table 3 Effects of test sample and controls on mice

From: Anxiolytic-like effect of Urena lobata (L.) in swiss albino mice

Treatment groups Open-field test (3 min) Light-dark test (3 min) Swing test (3 min)
Field cross Rearing Grooming Residence in light (Sec) Number of swings
NC (10 mL/kg, p.o.) 35.22 ± 0.87 7.08 ± 1.13 9.03 ± 1.25 153.13 ± 2.17 37.25 ± 2.19
DZP (2 mg/kg, i.p.) 17.05 ± 1.46* 3.57 ± 0.64* 4.41 ± 0.56* 56.12 ± 2.97* 9.33 ± 1.29*
MEUL (mg/kg, p.o.) 250 22.64 ± 1.75* 4.13 ± 1.28* 4.32 ± 1.64* 127.65 ± 2.87* 31.54 ± 2.63*
500 19.75 ± 2.61* 4.11 ± 2.03* 4.21 ± 1.29* 153.02 ± 2.43 21.12 ± 2.43*
  1. Values are the mean ± SEM (n = 5). ANOVA followed by Neuman Keuls test, *p < 0.05 when compared to NC group. NC Negative control (Vehicle: 0.05% tween 80 dissolved in 0.9% NaCl solution), DZP Diazepam, MEUL Methanol extract of U. lobata