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Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 3 Effects of test sample and controls on mice

From: Anxiolytic-like effect of Urena lobata (L.) in swiss albino mice

Treatment groups

Open-field test (3 min)

Light-dark test (3 min)

Swing test (3 min)

Field cross

Rearing

Grooming

Residence in light (Sec)

Number of swings

NC (10 mL/kg, p.o.)

35.22 ± 0.87

7.08 ± 1.13

9.03 ± 1.25

153.13 ± 2.17

37.25 ± 2.19

DZP (2 mg/kg, i.p.)

17.05 ± 1.46*

3.57 ± 0.64*

4.41 ± 0.56*

56.12 ± 2.97*

9.33 ± 1.29*

MEUL (mg/kg, p.o.)

250

22.64 ± 1.75*

4.13 ± 1.28*

4.32 ± 1.64*

127.65 ± 2.87*

31.54 ± 2.63*

500

19.75 ± 2.61*

4.11 ± 2.03*

4.21 ± 1.29*

153.02 ± 2.43

21.12 ± 2.43*

  1. Values are the mean ± SEM (n = 5). ANOVA followed by Neuman Keuls test, *p < 0.05 when compared to NC group. NC Negative control (Vehicle: 0.05% tween 80 dissolved in 0.9% NaCl solution), DZP Diazepam, MEUL Methanol extract of U. lobata
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