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International Journal of Phytomedicine and Phytotherapy

Table 4 Combined effects of the test sample and DZP in Swiss mice

From: Anxiolytic-like effect of Urena lobata (L.) in swiss albino mice

Treatment groups

Open-field test (3 min)

Light-dark test (3 min)

Swing test (3 min)

Field cross

Rearing

Grooming

Residence in light (Sec)

Number of swings

NC (10 mL/kg, p.o.)

35.22 ± 0.87

7.08 ± 1.13

9.03 ± 1.25

153.13 ± 2.17

37.25 ± 2.19

DZP

17.05 ± 1.46*

3.57 ± 0.64*

4.41 ± 0.56*

56.12 ± 2.97*

9.33 ± 1.29*

DZP2 + MEUL250

19.04 ± 2.03*#

3.39 ± 0.24*

4.01 ± 1.67*

141.61 ± 3.07*#

28.13 ± 1.03*#

DZP2 + MEUL500

23.05 ± 2.68*#

3.19 ± 1.07*#

3.04 ± 2.13*#

151.11 ± 2.39*#

34.01 ± 2.03*#

  1. Values are the mean ± SEM (n = 5). ANOVA followed by NeumanKeuls test, *p < 0.05 when compared to the NC group. NC: Negative control (Vehicle: 0.05% tween 80 dissolved in 0.9% NaCl solution). #p < 0.05 when compared to the positive control (DZP) group. DZP Diazepam, MEUL Methanol extract of U. lobata