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International Journal of Phytomedicine and Phytotherapy

Table 4 Combined effects of the test sample and DZP in Swiss mice

From: Anxiolytic-like effect of Urena lobata (L.) in swiss albino mice

Treatment groups Open-field test (3 min) Light-dark test (3 min) Swing test (3 min)
Field cross Rearing Grooming Residence in light (Sec) Number of swings
NC (10 mL/kg, p.o.) 35.22 ± 0.87 7.08 ± 1.13 9.03 ± 1.25 153.13 ± 2.17 37.25 ± 2.19
DZP 17.05 ± 1.46* 3.57 ± 0.64* 4.41 ± 0.56* 56.12 ± 2.97* 9.33 ± 1.29*
DZP2 + MEUL250 19.04 ± 2.03*# 3.39 ± 0.24* 4.01 ± 1.67* 141.61 ± 3.07*# 28.13 ± 1.03*#
DZP2 + MEUL500 23.05 ± 2.68*# 3.19 ± 1.07*# 3.04 ± 2.13*# 151.11 ± 2.39*# 34.01 ± 2.03*#
  1. Values are the mean ± SEM (n = 5). ANOVA followed by NeumanKeuls test, *p < 0.05 when compared to the NC group. NC: Negative control (Vehicle: 0.05% tween 80 dissolved in 0.9% NaCl solution). #p < 0.05 when compared to the positive control (DZP) group. DZP Diazepam, MEUL Methanol extract of U. lobata