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International Journal of Phytomedicine and Phytotherapy

Table 1 Characteristics of included studies

From: Efficacy, safety and phytochemistry of medicinal plants used for the management of diabetes mellitus in Ethiopia: a systematic review

No

Study

Study area

Name of plant (Scientific, family, local)

Model

1.

Amare et al., 2020 [35]

Fiche, oromia region

Aloe pulcherrima Gilbert and Sebsebe (Aloaceae)

Male Swiss albino mice

2.

Alema et al., 2020 [10]

Abiy Addi, Northwest Tigray

Terminalia brownie Fresen, Combretaceae, Abaloweyba (Am)

in vitro and STZ-induced mice

3.

Belayneh et al., 2018 [22]

South Gondar zone

Calpurnia aurea, Fabaceae, digita (Am)

STZ-induced albino mice

4.

Belayneh et al., 2019 [12]

Gondar town

Datura stramonium L. solanaceae, atefaris (Am)

STZ-induced diabetic mice

5.

Birru et al., 2015 [21]

Lake Tana

Indigofera spicata Forssk, Fabaceae, yeayitmisir (Am)

Alloxan-induced albino mice &wistar rats

6.

Gebremeskel et al., 2019 [6]

Mekelle

Trigonellafoenum-graecum, Fenugreek, Abish (Am)

T2DM

7.

Hammeso et al., 2019 [14]

SehartiSamre, Mekelle

Aloe megalacantha B, Aloaceae, Eret (Am)

STZ -induced mice

8.

Kifle & Eneyew, 2020 [34]

South Gondar

Bersama abyssinica Fresen, tena adam (Am)

Male Swiss albino mice

9.

Kifle et al., 2020 [32]

South Gondar

Bersama abyssinica Fresen

Male Swiss albino mice

10.

Makonnen et al., 1997 [17]

Arbaminch area

Moringa stenopetala, Moringaceae, shiferaw (Am), aleko (Welaytegna)

Albino rabbits

11.

Melaku and Amare et al.2020 [35]

Wollo, Amhara region

Datura stramonium Linn (Solanaceae)

Male Swiss albino mice

12.

Mussa et al., 2008 [11]

Arba Minch

Moringas stenopetalla

Alloxan-induced mice

13.

Nardos, et al., 2011 [23]

Arbaminch town

Moringa stenopetala, Moringaceae,Shiferaw (AM)/Haleko (GM)

Alloxan-induced mice

14.

Rao and Adinew 2011 [33]

Tepi,

Persea Americana, Laurel, Avocado

STZ induced rats

15.

Seifu et al., 2017 [27]

Southern, Ethiopia

Melia azedarachlinn, Meliaceae, Laylak (milya)

Ob/obmice and Rats

16.

Shewamene et al., 2015 [16]

Ayimba, Gondar, Ethiopia

Otostegia integrifolia, Lamiaceae, Tunzut

STZinduced Rat or mice

17.

Shewasinad et al., 2019 [26]

Gudoberet, North Shoa

Thymus schimperi, Lamiaceae, Tosign

STZ induced mice

18.

Sileshi et al 2014 [7]

Arbaminch town

Moringa Stenopetala,Moringaceae “Shiferaw (Am), Halekko (Wolita/gammo).”

Alloxan-induced Swiss albino mice

19.

Tafesse, etal 2017 [20]

Addis Ababa

Ajuga remota, Lamiaceae, Akorarach

Alloxan-induced mice

20.

Tamiru et al. 2012 [28]

Dirre, way from Bishoftu to Ziquala

Caylusea abyssinica (fresen.) fisch. &Mey. Resedaceae

STZ induced Swiss albino mice and Wistar rats

21.

Taye et al., 2020 [29]

Suluta, Oromia Region

Thymus schimperi (Lamiaceae)

Swiss albino mice

22.

Tefera et al., 2020 [30]

Woreta, Amhara region

L. culinaris

Swiss albino mice

23.

Tekulu et al. 2019 [25]

Tigray

Aloe megalacantha B.,Asphodelaceae, Aloe monticola R., Asphodelaceae“yedega ret. (Am)”

in vitro

24.

Tesfaye et al., 2016 [13]

Wolayta soddo, SNNPR

Justicia Schimperia naacanthaceae” Sensel or Simiza”

Normal andSTZ-induced mice

25.

Toma et al., 2012 [19]

Wolaitta zone, SNNPR

Moringa Stenopetala, Moringaceae “shiferaw Am” “HalekkoWo.”

Alloxan Induced mice

26.

Toma et al., 2014 [8]

GamoGofa Zone, SNNPR

Moringa Stenopetala,

in vitro

27.

Toma et al., 2015 [9]

GamoGofa Zone, SNNPR

Moringa Stenopetala

STZ-induced rats

28.

Tsegaye et al., 2008 [18]

Semen Mazegaja, Addis Ababa

UrticasimensisHochst. ex. A. Rich, “Samma”

STZ-induced mice

29.

Yibru et al., 2015 [15]

Addis Ababa

Coriandrum sativum, “dembellal”

STZ-induced mice

  1. Where; STZ streptozotocin, T2DM Type 2 Diabetes mellitus, Ob/ob obese mouse