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International Journal of Phytomedicine and Phytotherapy

Table 1 Characteristics of included studies

From: Efficacy, safety and phytochemistry of medicinal plants used for the management of diabetes mellitus in Ethiopia: a systematic review

No Study Study area Name of plant (Scientific, family, local) Model
1. Amare et al., 2020 [35] Fiche, oromia region Aloe pulcherrima Gilbert and Sebsebe (Aloaceae) Male Swiss albino mice
2. Alema et al., 2020 [10] Abiy Addi, Northwest Tigray Terminalia brownie Fresen, Combretaceae, Abaloweyba (Am) in vitro and STZ-induced mice
3. Belayneh et al., 2018 [22] South Gondar zone Calpurnia aurea, Fabaceae, digita (Am) STZ-induced albino mice
4. Belayneh et al., 2019 [12] Gondar town Datura stramonium L. solanaceae, atefaris (Am) STZ-induced diabetic mice
5. Birru et al., 2015 [21] Lake Tana Indigofera spicata Forssk, Fabaceae, yeayitmisir (Am) Alloxan-induced albino mice &wistar rats
6. Gebremeskel et al., 2019 [6] Mekelle Trigonellafoenum-graecum, Fenugreek, Abish (Am) T2DM
7. Hammeso et al., 2019 [14] SehartiSamre, Mekelle Aloe megalacantha B, Aloaceae, Eret (Am) STZ -induced mice
8. Kifle & Eneyew, 2020 [34] South Gondar Bersama abyssinica Fresen, tena adam (Am) Male Swiss albino mice
9. Kifle et al., 2020 [32] South Gondar Bersama abyssinica Fresen Male Swiss albino mice
10. Makonnen et al., 1997 [17] Arbaminch area Moringa stenopetala, Moringaceae, shiferaw (Am), aleko (Welaytegna) Albino rabbits
11. Melaku and Amare et al.2020 [35] Wollo, Amhara region Datura stramonium Linn (Solanaceae) Male Swiss albino mice
12. Mussa et al., 2008 [11] Arba Minch Moringas stenopetalla Alloxan-induced mice
13. Nardos, et al., 2011 [23] Arbaminch town Moringa stenopetala, Moringaceae,Shiferaw (AM)/Haleko (GM) Alloxan-induced mice
14. Rao and Adinew 2011 [33] Tepi, Persea Americana, Laurel, Avocado STZ induced rats
15. Seifu et al., 2017 [27] Southern, Ethiopia Melia azedarachlinn, Meliaceae, Laylak (milya) Ob/obmice and Rats
16. Shewamene et al., 2015 [16] Ayimba, Gondar, Ethiopia Otostegia integrifolia, Lamiaceae, Tunzut STZinduced Rat or mice
17. Shewasinad et al., 2019 [26] Gudoberet, North Shoa Thymus schimperi, Lamiaceae, Tosign STZ induced mice
18. Sileshi et al 2014 [7] Arbaminch town Moringa Stenopetala,Moringaceae “Shiferaw (Am), Halekko (Wolita/gammo).” Alloxan-induced Swiss albino mice
19. Tafesse, etal 2017 [20] Addis Ababa Ajuga remota, Lamiaceae, Akorarach Alloxan-induced mice
20. Tamiru et al. 2012 [28] Dirre, way from Bishoftu to Ziquala Caylusea abyssinica (fresen.) fisch. &Mey. Resedaceae STZ induced Swiss albino mice and Wistar rats
21. Taye et al., 2020 [29] Suluta, Oromia Region Thymus schimperi (Lamiaceae) Swiss albino mice
22. Tefera et al., 2020 [30] Woreta, Amhara region L. culinaris Swiss albino mice
23. Tekulu et al. 2019 [25] Tigray Aloe megalacantha B.,Asphodelaceae, Aloe monticola R., Asphodelaceae“yedega ret. (Am)” in vitro
24. Tesfaye et al., 2016 [13] Wolayta soddo, SNNPR Justicia Schimperia naacanthaceae” Sensel or Simiza” Normal andSTZ-induced mice
25. Toma et al., 2012 [19] Wolaitta zone, SNNPR Moringa Stenopetala, Moringaceae “shiferaw Am” “HalekkoWo.” Alloxan Induced mice
26. Toma et al., 2014 [8] GamoGofa Zone, SNNPR Moringa Stenopetala, in vitro
27. Toma et al., 2015 [9] GamoGofa Zone, SNNPR Moringa Stenopetala STZ-induced rats
28. Tsegaye et al., 2008 [18] Semen Mazegaja, Addis Ababa UrticasimensisHochst. ex. A. Rich, “Samma” STZ-induced mice
29. Yibru et al., 2015 [15] Addis Ababa Coriandrum sativum, “dembellal” STZ-induced mice
  1. Where; STZ streptozotocin, T2DM Type 2 Diabetes mellitus, Ob/ob obese mouse