Skip to main content

International Journal of Phytomedicine and Phytotherapy

Table 2 In vitro anti-diabetic activity of medicinal plants in Ethiopia

From: Efficacy, safety and phytochemistry of medicinal plants used for the management of diabetes mellitus in Ethiopia: a systematic review

Study Scientific name Parts used Extraction method Assay method Active cpd, Fraction / extraction IC50
Alema et al. 2020 [10] Terminalia brownii Fresen stem bark methanolic extract & solvent fractions α-Amylase Inhibition (chromogenic DNSA method) aqueous fraction > 100 μg/ml
Butanol fraction 84.69 μg/ml
chloroform fraction 63.41 μg/ml
ethyl acetate fraction > 100 μg/ml
crude extract > 100 μg/ml
Acarbose ~ 12.5 μg/ml
Kifle and Eneyew., 2020 [34] Bersama abyssinica leaf Methanolic Extraction α-Amylase Inhibition (chromogenic DNSA method) Chloroform fraction 30.97 + 0.84
Ethyl acetate fraction 20.34 + 0.67
Aqueous fraction 13.33 + 0.57
Crude extract 6.57 + 0.74
Acarbose 2.26 + 0.53
Toma et al. 2014 [8] Moringa Stenopetala powdered leaves ethanol extract Pancreatic α-amylase ethanol extract >  5 mg/ml
Maltase >  5 mg/ml
Pancreatic C. esterase >  5 mg/ml
Pancreatic lipase >  5 mg/ml
Sucrase 1.47 ± 0.19 mg/ml
Tekulu et al. 2019 [25] Aloe megalacantha B Aloe monticola R leaf Methanol extract α-Amylase Inhibition (chromogenic DNSA method) TLC fraction from A. megalacantha coded as AM1 37.83 ± 3.31 μg/mL
Leaf latex ofA. megalacantha 74.76 ± 1.98 μg/mL
TLC fraction from A. megalacantha coded as AM2 96.75 ± 1.98 μg/mL
Leaf latex ofA. monticola 78.10 ± 1.88 μg/mL
TLC fraction from A. monticola, AG1 56.95 ± 1.88 μg/mL
TLC fraction from A. monticola, AG2 64.03 ± 3.60 μg/mL
Acarbose 16.49 ± 1.91 μg/mL