International Journal of Phytomedicine and Phytotherapy
Table 2 Wound healing properties of some peels and seed extracts
From: Phytowaste as nutraceuticals in boosting public health
Plants | Bioactive compounds | Test organism | Conc/body weight | Therapeutic activities | Mechanism of action | References |
|---|---|---|---|---|---|---|
M. paradisiaca peel | alkaloids and tannins, saponins and phenols | Rats | 100 mg/kg | Wound healing | Complete epithelialization through elevation of collagen fibers and fibroblast cellular infiltration, the extract showed more proliferating blood capillaries | Padilla-Camberos et al [45] |
Pomegranate seed | gallic acid, catechin and saponins | Rabbit | 100 mg/kg | Wound healing | Elevated CAT activity and GSH concentrations | [49] |
C. moschata Duchesne fruit. Pumpkin peel | gallic acid | Wistar rats | 10% and 20% | burn wound healing activity | immunomodulatory activity through increase in natural killer cells and splenic lymphocyte proliferation | [52] |
(Musa sapientum Linn. Var. compressa) Saba Banana peel | Leucocyanidin | Sparague Dawley Rats | 50–100% extract | Skin wound healing, anti-hemorrhagic | increased concentration of collagen fibers, reduced vascular proliferation and Reduced wound contraction, | |
P. granatum peel | gallic acid, catechin, saponins, triterpenes, sterols, tannins, alkaloids, flavonoids and cardiac glycosides | Rats | 10% (wt/wt) 100 mg/kg/day for 15 days | wound healing activity | fasten the process of healing improved histopathological parameters through the precipitation of proteins from animal hide. Reduced the number of immune cells, accelerating the second stage of the healing, and the migration of fibroblast to the wounded tissue. | |
Grape seed and peel | proanthocyanidins | 2% | wound healing | shortening the healing by enhancing the process of contraction and closure of wounds, time | ||
M. acuminata Colla AAA) peel | biogenic amines, L-dopa and dopamine | 5 mg | Antihemolytic Activity |