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International Journal of Phytomedicine and Phytotherapy

Fig. 1 | Clinical Phytoscience

Fig. 1

From: Toxicity study and anti-trypanosomal activities of aqueous and methanol whole plant extracts of Brillantaisia owariensis on Trypanosoma brucei-induced infection in BALB/c mice

Fig. 1

Plate 1(a-f): Toxicity of aqueous and methanol whole plant extracts of Brillantaisia owariensis on the histology of Liver organ in BALB/c mice at lower and higher dosages. a Moderate hepatic necrosis at doses of A10 mg/Kg/body weights of aqueous and methanol extracts. b Mild vascular congestion at 100 mg/Kg aqueous extract, and moderate hepatic necrosis in mice orally administered 100 mg/Kg/ body weight of the methanol extracts. c Mild vascular congestion and lymphocyte hyperplasia in mice administered 1000 mg/kg aqueous and methanol extract. d Vascular congestion and slight hepatic necrosis and lymphocyte hyperplasia at 1600 mg/kg aqueous and methanol extract e Lymphocyte hyperplasia at 2500 mg/Kg/ body weight of both aqueous and methanol extract. f Mild vascular congestion and moderate hepatic necrosis at 5000 mg/Kg/body weight of aqueous and methanol extracts. (H and E, X 400)

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