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International Journal of Phytomedicine and Phytotherapy

Table 1 IC50 values of the plant extracts against 3D7 and RKL-9 strains of P. falciparum

From: In vitro antimalarial activity evaluation of two ethnomedicinal plants against chloroquine sensitive and resistant strains of Plasmodium falciparum

Sl. No. Samples IC50a (μg/ml)
Plant Solvent for extraction 3D7 RKL-9
1 C. maxima Petroleum ether (PE) 27.25 ± 1.52 42.70 ± 0.14
Chloroform (Chlor) 7.20 ± 0.16 11.74 ± 0.01
Ethyl acetate (EA) 5.87 ± 0.19 6.19 ± 0.22
Methanol (ME) 3.52 ± 0.32 4.52 ± 0.19
Hydro-alcoholic (HA) 3.41 ± 0.31 4.45 ± 0.10
Remedy (REM) 20.77 ± 1.30 31.19 ± 2.29
2 A. nilagirica Petroleum ether (PE) 14.24 ± 0.25 18.65 ± 0.67
Chloroform (Chlor) 11.61 ± 1.26 14.51 ± 0.26
Ethyl acetate (EA) 5.22 ± 0.14 5.75 ± 0.23
Methanol (ME) 3.28 ± 0.08 3.81 ± 0.34
Hydro-alcoholic (HA) 3.41 ± 0.11 5.51 ± 0.39
Remedy (REM) 26.51 ± 1.35 37.86 ± 3.17
3 Standard drug (Chloroquine phosphate) 0.54 ± 0.02 0.88 ± 0.04
  1. aThe IC50 values (Mean ± SD) were calculated from triplicate analysis