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International Journal of Phytomedicine and Phytotherapy

Table 1 IC50 values of the plant extracts against 3D7 and RKL-9 strains of P. falciparum

From: In vitro antimalarial activity evaluation of two ethnomedicinal plants against chloroquine sensitive and resistant strains of Plasmodium falciparum

Sl. No.

Samples

IC50a (μg/ml)

Plant

Solvent for extraction

3D7

RKL-9

1

C. maxima

Petroleum ether (PE)

27.25 ± 1.52

42.70 ± 0.14

Chloroform (Chlor)

7.20 ± 0.16

11.74 ± 0.01

Ethyl acetate (EA)

5.87 ± 0.19

6.19 ± 0.22

Methanol (ME)

3.52 ± 0.32

4.52 ± 0.19

Hydro-alcoholic (HA)

3.41 ± 0.31

4.45 ± 0.10

Remedy (REM)

20.77 ± 1.30

31.19 ± 2.29

2

A. nilagirica

Petroleum ether (PE)

14.24 ± 0.25

18.65 ± 0.67

Chloroform (Chlor)

11.61 ± 1.26

14.51 ± 0.26

Ethyl acetate (EA)

5.22 ± 0.14

5.75 ± 0.23

Methanol (ME)

3.28 ± 0.08

3.81 ± 0.34

Hydro-alcoholic (HA)

3.41 ± 0.11

5.51 ± 0.39

Remedy (REM)

26.51 ± 1.35

37.86 ± 3.17

3

Standard drug (Chloroquine phosphate)

0.54 ± 0.02

0.88 ± 0.04

  1. aThe IC50 values (Mean ± SD) were calculated from triplicate analysis