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International Journal of Phytomedicine and Phytotherapy

Table 2 In vivo anthelmintic effects of A. racemosus root extract* on S. obvelata infections in mice (n = 5)

From: Studies on the anthelmintic potentials of the roots of Asparagus racemosus willd. (Asparagaceae)

Treatment groups (mg/kgxdosexday) EPG (mean ± SEM) Percentage difference in EPG Worm count at necropsy Percentage reduction in worm count
Pre-treatment (days 1–3) Post-treatment (days 9–11) Min – Max Mean ± SEM
Control 26.8 ± 1.15 27.8 ± 0.37 3.7 64–117 91.8 ± 9.00 0
Plant extract
125 × 1 × 5 20.6 ± 0.74 17.6 ± 2.15 −14.56 46–91 71.2 ± 7.80 22.44
250 × 1 × 5 25.4 ± 1.32 21.2 ± 3.2 −16.53 41–102 67.6 ± 10.50 26.36
500 × 1 × 5 24.8 ± 1.85 18.2 ± 3.39 −26.61 36–99 63.4 ± 11.61 30.93
Albendazole
20 × 1 × 5 28.0 ± 0.70 6 ± 0.70b −78.57 5–6 5.4 ± 0.24a 94.11
  1. *Administration of plant extract and albendazole on days 4–8 after pre-treatment EPG
  2. ap<0.001 as compared to control value, bp<0.001 as compared to pre-treatment period, one-way ANOVA, followed by Tukey’s test