Table 1 Effect of n-hexane, chloroform and methanol soluble fractions of Sargassum ilicifolium on liver enzymes and bilirubin in normal and acetaminophen (AAP) dosed rats

Control

33.6^ab ± 3.5

104.6 ^a ± 9.4

134.3^c ± 6

239.3^b ± 8.1

67.6^a ± 6.5

113.6^a ± 10.4

328.6^a ± 10

396.3^a ± 6

0.4^a ± 0

0.86^a ± 0.06

hexane fraction of S. ilicifolium

30.3^b ± 2.3 (−9.8%)

63^b ± 2.6   (− 39.7%)

166.3^b ± 8.6 (+ 23.8%)

178.3^c ± 9.6 (−25.4%)

74^a ± 3   (+ 9.4%)

87.3^b ± 2.1 (− 23.1%)

312.6^b ± 4.5 (− 4.8%)

303.3^b ± 22  (− 23.4%)

0.46^a ± 0.1 (+ 15%)

0.6^b ± 0.1   (− 30.2%)

Chloroform fraction of S. ilicifolium

38.3^a ± 3.5 (+ 13.9%)

99.6^a ± 17 (− 4.7%)

237.6^a ± 19.4 (+ 76.9%)

295.3^a ± 8  (+ 23.4%)

67.6^a ± 3.5 (0)

106.6^a ± 6.5 (− 6.16%)

298^b ± 7    (− 9.3%)

303^b ± 8      (− 23.5%)

0.43^a ± 0.05 (+ 7.5%)

0.66^b ± 0.06 (− 23.2%)

Methanol fraction of S. ilicifolium

35.6^ab ± 3.2 (+ 5.9%)

66.6^b ± 2.5 (− 36.3%)

180.3^b ± 4.5 (+ 34.2%)

182.3^c ± 13 (− 23.8%)

71^a ± 2.6 (+ 5.0%)

79.6^b ± 2    (− 29.9%)

312.6^b ± 9 (− 4.86%)

331.3^b ± 19.6 (− 16.4%)

0.46^a ± 0   (+ 15%)

0.53^b ± 0.06 (− 38.3%)