Skip to main content

International Journal of Phytomedicine and Phytotherapy

Table 2 Effect of n-hexane, chloroform and methanol soluble fractions of Sargassum ilicifolium on glucose, lipid parameters and kidney function markers in normal and acetaminophen dosed rats

From: Hepatoprotective activity against acetaminophen-induced liver dysfunction and GC-MS profiling of a brown algae Sargassum ilicifolium

Rat groups Normal rats AAP dosed rats Normal rats AAP dosed rats Normal
rats
AAP dosed rats Normal
Rats
AAP dosed rats Normal rats AAP dosed rats
  Glucose (mg/dl) Triglyceride (mg/dl) Cholesterol (mg/dl) Urea (mg/dl) Creatinine (mg/dl)
Control 83.6a ± 4.7 169.6a ± 8.7 74.3b ± 5.1 104.3b ± 1.5 73.6b ± 6.8 55.6b ± 2.08 26.3a ± 2.5 42a ± 2 0.83b ± 0.06 1.3a ± 0.1
hexane fraction of S. ilicifolium 81a ± 5.5 (− 3.11%) 131.3b ± 3.2 (− 22.5%) 75.6b ± 4.9   (+ 1.7%) 110.3b ± 4  (+ 5.75%) 75.6b ± 6.4 (+ 2.71%) 73.6a ± 2.8 (+ 32.3%) 25.6a ± 1.5 (− 2.66%) 29b ± 2.6 (− 30.9%) 0.96a ± 0.06 (+ 15.6%) 0.9b ± 0.1    (− 30.7%)
Chloroform fraction of S. ilicifolium 71.6b ± 3.7 (− 14.3%) 154.3a ± 15.6 (− 9.0%) 91.6a ± 3.7   (+ 23.2%) 109.6b ± 4.6 (+ 5.08%) 81.3b ± 3.2 (+ 10.4%) 56.3b ± 5.5 (+ 1.25%) 28.6a ± 1.15 (+ 8.7%) 39a ± 1    (− 7.14%) 0.92ab ± 0.05 (+ 10.8%) 1.23a ± 0.06 (− 5.38%)
Methanol fraction of S. ilicifolium 63c ± 3.6   (− 24.6%) 118b ± 5.2  (− 30.4%) 87.6ab ± 11.06 (+ 17.9%) 123a ± 5     (+ 17.9%) 92.3a ± 3.2 (+ 25.4%) 68.3a ± 4.6 (+ 22.8%) 26a ± 2.6   (− 1.14%) 25c ± 2    (− 40.4%) 1.03a ± 0.05 (+ 24.0%) 0.96b ± 0.06 (− 26.15%)
  1. The values were expressed as means ± Standard error (n = 6)
  2. The values having the same superscript within the column are not significantly (p < 0.05) different according to Duncan’s multiple range test
  3. Values in parenthesis are showing percent increased or decreased as compared to their respective control