Table 2 Effect of n-hexane, chloroform and methanol soluble fractions of Sargassum ilicifolium on glucose, lipid parameters and kidney function markers in normal and acetaminophen dosed rats

Control

83.6^a ± 4.7

169.6^a ± 8.7

74.3^b ± 5.1

104.3^b ± 1.5

73.6^b ± 6.8

55.6^b ± 2.08

26.3^a ± 2.5

42^a ± 2

0.83^b ± 0.06

1.3^a ± 0.1

hexane fraction of S. ilicifolium

81^a ± 5.5 (− 3.11%)

131.3^b ± 3.2 (− 22.5%)

75.6^b ± 4.9   (+ 1.7%)

110.3^b ± 4  (+ 5.75%)

75.6^b ± 6.4 (+ 2.71%)

73.6^a ± 2.8 (+ 32.3%)

25.6^a ± 1.5 (− 2.66%)

29^b ± 2.6 (− 30.9%)

0.96^a ± 0.06 (+ 15.6%)

0.9^b ± 0.1    (− 30.7%)

Chloroform fraction of S. ilicifolium

71.6^b ± 3.7 (− 14.3%)

154.3^a ± 15.6 (− 9.0%)

91.6^a ± 3.7   (+ 23.2%)

109.6^b ± 4.6 (+ 5.08%)

81.3^b ± 3.2 (+ 10.4%)

56.3^b ± 5.5 (+ 1.25%)

28.6^a ± 1.15 (+ 8.7%)

39^a ± 1    (− 7.14%)

0.92^ab ± 0.05 (+ 10.8%)

1.23^a ± 0.06 (− 5.38%)

Methanol fraction of S. ilicifolium

63^c ± 3.6   (− 24.6%)

118^b ± 5.2  (− 30.4%)

87.6^ab ± 11.06 (+ 17.9%)

123^a ± 5     (+ 17.9%)

92.3^a ± 3.2 (+ 25.4%)

68.3^a ± 4.6 (+ 22.8%)

26^a ± 2.6   (− 1.14%)

25^c ± 2    (− 40.4%)

1.03^a ± 0.05 (+ 24.0%)

0.96^b ± 0.06 (− 26.15%)